Background Pancreatic ductal adenocarcinoma (PDA) is characterised by a robust desmoplasia,
including the notable accumulation of immunosuppressive cells that shield neoplastic …

Pancreatic ductal adenocarcinomas (PDAs) erect physical barriers to chemotherapy and
induce multiple mechanisms of immune suppression, creating a sanctuary for unimpeded …

Objectives: A. Identify the current state of data management needs of academic biomedical
researchers. B. Explore their anticipated data management and analysis needs. C. Identify …

Elevated interstitial fluid pressure can present a substantial barrier to drug delivery in solid
tumors. This is particularly true of pancreatic ductal adenocarcinoma, a highly lethal disease …

As we have previously shown, by 8 wk after 90% pancreatectomy (PX) in the rat, there is
considerable regeneration of both exocrine and endocrine pancreas. In this study we examine …

To investigate the function of the nucleolar protein Nop2p in Saccharomyces cerevisiae, we
constructed a strain in which NOP2 is under the control of a repressible promoter. …

Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to therapies, including
immune-checkpoint blockade. We investigated two distinct strategies to modulate tumor-…

We have identified a novel nucleolar protein, Nop5p, that is essential for growth in Saccharomyces
cerevisiae. Monoclonal antibodies B47 and 37C12 recognize Nop5p, which has a …

The nucleolar protein Nop2p is an essential gene product that is required for pre-rRNA
processing and ribosome biogenesis in Saccharomyces cerevisiae (Hong, B. et al., 1997, Mol. …

We report the first, to our knowledge, findings describing the relationships between both static
and dynamic analysis parameters of 3′-deoxy-3′- 18 F-fluorothymidine ( 18 F-FLT) PET …