User profiles for Jörg Hamann

Jörg Hamann

Principal Investigator and Head of Biobank, Amsterdam University Medical Centers
Verified email at amsterdamumc.nl
Cited by 14261

The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors

…, KJ Gregory, AL Gundlach, J Hamann… - British journal of …, 2021 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors

…, KJ Gregory, AL Gundlach, J Hamann… - British journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

…, NA Kootstra, J Hamann… - Blood, The Journal …, 2013 - ashpublications.org
The molecular repertoire of macrophages in health and disease can provide novel biomarkers
for diagnosis, prognosis, and treatment. Th2-IL-4–activated macrophages (M2) have …

International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors

J Hamann, G Aust, D Araç, FB Engel, C Formstone… - Pharmacological …, 2015 - ASPET
The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

[HTML][HTML] Clinical features and prognostic factors in Covid-19: a prospective cohort study

…, PR Tuinman, MA van Agtmael, J Hamann… - …, 2021 - thelancet.com
Background Mortality rates are high among hospitalized patients with COVID-19, especially
in those intubated on the ICU. Insight in pathways associated with unfavourable outcome …

Serine proteases of the human immune system in health and disease

KM Heutinck, IJM ten Berge, CE Hack, J Hamann… - Molecular …, 2010 - Elsevier
Serine proteases form a large family of protein-cleaving enzymes that play an essential role
in processes like blood coagulation, apoptosis and inflammation. Immune cells express a …

[HTML][HTML] Tissue-resident memory T cells populate the human brain

…, RAW van Lier, I Huitinga, J Hamann - Nature …, 2018 - nature.com
Most tissues are populated by tissue-resident memory T cells (T RM cells), which are adapted
to their niche and appear to be indispensable for local protection against pathogens. Here …

Sticky signaling—adhesion class G protein–coupled receptors take the stage

T Langenhan, G Aust, J Hamann - Science signaling, 2013 - science.org
Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …

Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology

…, CG van Eden, KG Schuurman, J Hamann… - Journal of …, 2017 - Elsevier
HLA-DR, Iba1 and CD68 are widely used microglia markers in human tissue. However, due
to differences in gene regulation, they may identify different activation stages of microglia. …

[HTML][HTML] Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

…, B Helder, SW Tas, JL Schultze, J Hamann… - Nature …, 2019 - nature.com
Here we report the transcriptional profile of human microglia, isolated from normal-appearing
grey matter (GM) and white matter (WM) of multiple sclerosis (MS) and non-neurological …