Amyloid imaging with 18F-florbetaben in Alzheimer disease and other dementias

…, H Tochon-Danguy, JG Chan… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Amyloid imaging with 18 F-labeled radiotracers will allow widespread use, facilitating research,
diagnosis, and therapeutic development for Alzheimer disease. The purpose of the study …

Comparison of 11C-PiB and 18F-florbetaben for Aβ imaging in ageing and Alzheimer's disease

…, K Ong, G Jones, G O'Keefe, JG Chan… - European journal of …, 2012 - Springer
Purpose Amyloid imaging with 18 F-labelled radiotracers will allow widespread use of this
technique, facilitating research, diagnosis and therapeutic development for Alzheimer’s …

Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for β-amyloid imaging in aging and dementia

…, RS Mulligan, G Jones, JG Chan… - Journal of Nuclear …, 2013 - Soc Nuclear Med
11 C-Pittsburgh compound-B ( 11 C-PiB) is the benchmark radiotracer for imaging of β-amyloid
(Aβ) plaque in Alzheimer disease (AD). F-labeled Aβ tracers subsequently developed for …

Evaluation of 18F-fluorodeoxyglucose positron emission tomography and computed tomography with histopathologic correlation in the initial staging of head and neck …

…, AM Scott, H Tochon-Danguy, JG Chan… - Annals of …, 2002 - journals.lww.com
Objective To prospectively evaluate the use of 18 F-Fluorodeoxyglucose positron emission
tomography (FDG-PET) in the initial staging of squamous cell head and neck carcinoma. …

The fate of hypoxic tissue on 18F‐fluoromisonidazole positron emission tomography after ischemic stroke

…, HJ Tochon‐Danguy, JG Chan… - Annals of Neurology …, 2000 - Wiley Online Library
We studied 24 patients up to 51 hours after ischemic stroke using 18 F‐fluoromisonidazole
positron emission tomography to determine the fate of hypoxic tissue likely to represent the …

Standardized expression of 18F-NAV4694 and 11C-PiB β-amyloid PET results with the Centiloid scale

…, L Margison, RS Mulligan, JG Chan… - Journal of Nuclear …, 2016 - Soc Nuclear Med
A common quantitative output value for PET measures of β-amyloid (Aβ) binding across
tracers and methods would allow better comparison of data across sites and application of …

Radiation dosimetry of β-amyloid tracers 11C-PiB and 18F-BAY94-9172

…, HJ Tochon-Danguy, JG Chan… - Journal of Nuclear …, 2009 - Soc Nuclear Med
β-Amyloid (Aβ) imaging has great potential to aid in the diagnosis of Alzheimer disease and
the development of therapeutics. The radiation dosimetry of Aβ radioligands may influence …

Relationship between nicotinic receptors and cognitive function in early Alzheimer's disease: a 2-[18F] fluoro-A-85380 PET study

…, RS Mulligan, SJ Gong, JG Chan, J Sachinidis… - Neurobiology of learning …, 2008 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are critical for higher order cognitive
processes. Post-mortem studies suggest reductions in nAChRs (particularly the α 4 β 2 subtype…

Imaging and quantitation of the hypoxic cell fraction of viable tumor in an animal model of intracerebral high grade glioma using [18F] fluoromisonidazole (FMISO)

…, F Chan, JG Chan, C Hall, L Cher, S Stylli, J Hill… - Nuclear medicine and …, 2002 - Elsevier
We have demonstrated that FMISO uptake is significantly higher in tumor tissue in the C6
intracerebral glioma rat model compared to normal brain, and that there is persisting hypoxia in …

[PDF][PDF] Ictal SPECT using technetium-99m-HMPAO: methods for rapid preparation and optimal deployment of tracer during spontaneous seizures

MR Newton, MC Austin, JG Chan… - Journal of Nuclear …, 1993 - Soc Nuclear Med
Storage and Radiation Safety. The 5 ml luer-lock syringe, preloaded with sodium pertechnetate,
is covered with a syringe shield and placed in a stainless steel lead-lined syringe carrier…