[PDF][PDF] Optimal radiolabeled liposomes for tumor imaging

I Ogihara-Umeda, T Sasaki, S Kojima… - Journal of Nuclear …, 1996 - Soc Nuclear Med
OptimalRadiolabeledLiposomesforTumorJmaging Page 1 ratios. In this study, we therefore
first examined various liposome formulations and encapsulatedradionuclides in relation to …

Molecular therapy of human neuroblastoma cells using Auger electrons of 111In-labeled N-myc antisense oligonucleotides

N Watanabe, H Sawai, I Ogihara-Umeda… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Auger electrons can create breaks in nucleic acids, giving them possible therapeutic utility.
We investigated the therapeutic effect of Auger electrons emitted by 111 In-labeled …

Rapid diagnostic imaging of cancer using radiolabeled liposomes.

I Ogihara-Umeda, T Sasaki, H Toyama… - Cancer detection and …, 1997 - europepmc.org
A novel tumor diagnostic imaging method was developed that allows tumor localization
soon after administration of radiolabeled liposomes. Although previous studies showed that …

[PDF][PDF] Increased delivery of gallium-67 to tumors using serum-stable liposomes

I Ogihara-Umeda, S Kojima - Journal of nuclear medicine, 1988 - Soc Nuclear Med
Gallium-67 chelated to nitrilotriacetic acid was encapsulated inliposomes composed of
various phospholipids, and Â7Gadelivery potential to the tumor after intravenous injection of …

Cholesterol enhances the delivery of liposome-encapsulated gallium-67 to tumors

I Ogihara-Umeda, S Kojima - European journal of nuclear medicine, 1989 - Springer
The effect of incorporation of cholesterol (CH) into liposome membranes on the delivery of 67
Ga encapsulated in liposomes to tumors was studied. The changes of the blood clearance …

Development of a liposome-encapsulated radionuclide with preferential tumor accumulation—the choice of radionuclide and chelating ligand

I Ogihara-Umeda, T Sasaki, H Nishigori - International journal of radiation …, 1992 - Elsevier
Various radionuclide-ligand complexes were encapsulated in liposomes and their
accumulations in tumors were studied. Increased tumor accumulation was observed with every …

Rapid tumor imaging by active background reduction using biotin-bearing liposomes and avidin

I Ogihara-Umeda, T Sasaki, H Toyama, K Oda… - Cancer research, 1994 - AACR
Tumor imaging with labeled liposomes is slow; although they reach the tumor quickly, their
blood clearance is slow, and the high blood background hinders early imaging. We have …

Active removal of radioactivity in the blood circulation using biotin-bearing liposomes and avidin for rapid tumour imaging

I Ogihara-Umeda, T Sasaki, H Nishigori - European journal of nuclear …, 1993 - Springer
In order to shorten the delay between the administration of tumour-imaging agents and
obtainment of scintigrams, rapid delivery of radionuclide to tumours followed by rapid clearance …

[PDF][PDF] Assessment of antioxidative ability in brain: Technetium-99m-meso-HMPAO as an imaging agent for glutathione localization

…, H Toyama, K Oda, I Ogihara-Umeda… - Journal of Nuclear …, 1996 - Soc Nuclear Med
RESULTS Figure 1shows the relationship between the content of GSH and the uptake of
[99mTc] weso-or £/,/-HMPAOin the mouse brain. Increasing the load of DEM led to a dose …

Involvement of hepatic glucocorticoid receptor-mediated functions in steroid-induced cataract formation

…, H Kosano, S Nakai, I Ogihara-Umeda… - Experimental eye …, 2003 - Elsevier
Determination of whether the steroid-induced cataract formation is caused through glucocorticoid
(GC) receptor-mediated process was conducted by using GC antagonist (RU486) and …