Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes

…, HP Kothari, ZA Qadeer, IM Germano - Stem cells and …, 2012 - liebertpub.com
Human high-grade gliomas (hHGG) remain a therapeutic challenge in neuro-oncology despite
current multimodality treatments. We recently demonstrated that murine embryonic stem …

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide

T Kanzawa, Y Kondo, H Ito, S Kondo, I Germano - Cancer research, 2003 - AACR
Recent clinical data shows that arsenic trioxide (As 2 O 3 ) causes remission in patients with
acute promyelocytic leukemia and multiple myeloma without severe side effects. Laboratory …

Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat

JB Bederson, IM Germano, L Guarino - Stroke, 1995 - Am Heart Assoc
Background and Purpose Acute cerebral ischemia after subarachnoid hemorrhage (SAH) is
a major cause of morbidity whose precise etiology is unclear. The purpose of this study was …

Intracranial meningiomas of the first two decades of life

IM Germano, MSB Edwards, RL Davis… - Journal of neurosurgery, 1994 - thejns.org
✓ Meningiomas arising in the first two decades of life are uncommon and their characteristics
are controversial. Some authors believe meningiomas in younger patients occur in …

Tracking career paths of women in neurosurgery

JJ Renfrow, A Rodriguez, TA Wilson, IM Germano… - …, 2018 - journals.lww.com
METHODS Databases from the American Association of Neurological Surgeons (AANS) and
the American Board of Neurological Surgery (ABNS) from 1964 to 2013 were reviewed for …

Decompressive craniectomy for severe traumatic brain injury: a systematic review

…, M Melis, E Gordon, JS Ullman, IM Germano - World neurosurgery, 2016 - Elsevier
Objective Systematic review of the literature to evaluate the role of decompressive craniectomy
(DC) after severe traumatic brain injury (TBI), comparing the first major randomized …

ACR appropriateness criteria follow-up of malignant or aggressive musculoskeletal tumors

…, M Appel, SA Bernard, IB Fries, IM Germano… - Journal of the American …, 2016 - Elsevier
Appropriate imaging modalities for the follow-up of malignant or aggressive musculoskeletal
tumors include radiography, MRI, CT, 18 F-2-fluoro-2-deoxy-D-glucose PET/CT, 99m Tc …

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3

T Kanzawa, L Zhang, L Xiao, IM Germano, Y Kondo… - Oncogene, 2005 - nature.com
Arsenic trioxide (As 2 O 3) has shown considerable efficacy in treating hematological
malignancies with induction of programmed cell death (PCD) type I, apoptosis. However, the …

The future of neurosurgery: a white paper on the recruitment and retention of women in neurosurgery

DL Benzil, A Abosch, I Germano, H Gilmer… - Journal of …, 2008 - thejns.org
Preface The leadership of Women in Neurosurgery (WINS) has been asked by the Board of
Directors of the American Association of Neurological Surgeons (AANS) to compose a white …

Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of cyclin-dependent kinase inhibitors, and autophagy

…, Y Kondo, T Kanzawa, S Kondo, IM Germano - Journal of …, 2003 - thejns.org
Object. Ionizing radiation is the gold-standard adjuvant treatment for glioblastoma multiforme
(GBM), the most aggressive primary brain tumor. The mechanisms underlying neoplastic …