Genome-wide association studies (GWAS) have laid the foundation for investigations into the
biology of complex traits, drug development and clinical guidelines. However, the majority …

Prostate cancer (CaP) is the leading cancer among men of African descent in the USA,
Caribbean, and Sub-Saharan Africa (SSA). The estimated number of CaP deaths in SSA during …

Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide
deaths, respectively, due largely to broad increased risk for disease and injury 1 , 2 , 3 – …

In search of common risk alleles for prostate cancer that could contribute to high rates of the
disease in men of African ancestry, we conducted a genome-wide association study, with …

Background The racial/ethnic disparities in prostate cancer rates are well documented, with
the highest incidence and mortality rates observed among African-Americans followed by …

Background Prostatitis and sexually transmitted diseases (STDs) have been positively
associated with prostate cancer in previous case-control studies. However, results from recent …

Background Previous genome-wide association studies (GWAS) have identified 42 loci (P <
5 × 10 −8 ) associated with risk of colorectal cancer (CRC). Expanded consortium efforts …

Purpose: Dietary intake of long-chain ω-3 (LC n-3) polyunsaturated fatty acids may reduce
inflammation and in turn decrease risk of prostate cancer development and progression. This …

Background Trimethylamine N-oxide (TMAO), a compound derived from diet and metabolism
by the gut microbiome, has been associated with several chronic diseases, although the …

Genome-wide association studies (GWAS) have identified ∼100 loci associated with blood
lipid levels, but much of the trait heritability remains unexplained, and at most loci the …