Quantitative baseline renography 48 hours after renal transplantation predicts long-term graft survival

H Stevens, JM Klerk, IJ Mertens, PP Rijk… - European journal of …, 2001 - Springer
Technetium-99m mercaptoacetylglycine ( 99m Tc-MAG3) renography is a successful non-invasive
method for the evaluation of renal transplants. In this study we prospectively studied …

[PDF][PDF] Fluorine-18-FDG detection of laryngeal cancer postradiotherapy using dual-head coincidence imaging

MP Stokkel, CH Terhaard, IJ Mertens… - Journal of Nuclear …, 1998 - Soc Nuclear Med
RESULTS The mean plasma glucose level in this study was 4.6 mmol/liter (range 4.2-6.2
mmol/liter). Fluorine-18-FDG PET scans were positive in all six patients with local relapse as …

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

…, P Lefebvre, MR Taskinen, W Van Hul, I Mertens… - Journal of …, 2015 - Elsevier
Background & Aims Peroxisome proliferator-activated receptors (PPARs) have been implicated
in non-alcoholic steatohepatitis (NASH) pathogenesis, mainly based on animal data. …

Mechanisms linking obesity with cardiovascular disease

LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com
Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue
releases a large number of bioactive mediators that influence not only body weight …

[PDF][PDF] Prothrombotic factors in histologically proven nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

A Verrijken, S Francque, I Mertens, J Prawitt… - …, 2014 - Wiley Online Library
An independent role of nonalcoholic fatty liver disease (NAFLD) in the development of
cardiovascular disease has been suggested, probably mediated through increased levels of …

Noninvasive assessment of nonalcoholic fatty liver disease in obese or overweight patients

SMA Francque, A Verrijken, I Mertens, G Hubens… - Clinical …, 2012 - Elsevier
BACKGROUND & AIMS: Reliable noninvasive tools are needed for staging nonalcoholic fatty
liver disease (NAFLD). Published scoring systems have not been validated in prospective …

Association of the BDNF Val66Met variation with obesity in women

S Beckers, A Peeters, D Zegers, I Mertens… - Molecular genetics and …, 2008 - Elsevier
Brain-derived neurotrophic factor (BDNF) has been implied in the regulation of food intake.
In the present study, we genotyped the Val66Met polymorphism in a Belgian cohort of 532 …

Association between polymorphisms of the Nesfatin gene, NUCB2, and obesity in men

D Zegers, S Beckers, IL Mertens, LF Van Gaal… - Molecular Genetics and …, 2011 - Elsevier
Nesfatin-1, which originates from its precursor protein nucleobindin-2 (NUCB2), is a novel
appetite-regulating molecule that might be associated with the melanocortin signalling …

What is the relationship between risk factor reduction and degree of weight loss?

LF Van Gaal, IL Mertens… - European Heart Journal …, 2005 - academic.oup.com
Moderate weight loss achieved through lifestyle interventions positively impacts on a number
of metabolic and cardiovascular risk factors. Clinical studies have shown that sustained …

Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia

S Caron, A Verrijken, I Mertens… - … , and vascular biology, 2011 - Am Heart Assoc
Objective— Hypertriglyceridemia and fatty liver are common in patients with type 2 diabetes,
but the factors connecting alterations in glucose metabolism with plasma and liver lipid …