Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia
CM Adler, AK Malhotra, I Elman… - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: This study sought to determine whether thought disorder induced in healthy
volunteers by the N-methyl-d-aspartic acid (NMDA) receptor antagonist ketamine resembles …
volunteers by the N-methyl-d-aspartic acid (NMDA) receptor antagonist ketamine resembles …
[PDF][PDF] Common brain mechanisms of chronic pain and addiction
I Elman, D Borsook - Neuron, 2016 - cell.com
While chronic pain is considered by some to be a CNS disease, little is understood about
underlying neurobiological mechanisms. Addiction models have heuristic value in this regard, …
underlying neurobiological mechanisms. Addiction models have heuristic value in this regard, …
Pain and suicidality: insights from reward and addiction neuroscience
I Elman, D Borsook, ND Volkow - Progress in neurobiology, 2013 - Elsevier
Suicidality is exceedingly prevalent in pain patients. Although the pathophysiology of this
link remains unclear, it may be potentially related to the partial congruence of physical and …
link remains unclear, it may be potentially related to the partial congruence of physical and …
Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics
AK Malhotra, DA Pinals, CM Adler, I Elman… - …, 1997 - Elsevier
The N-methyl-d-aspartate (NMDA) receptor has been implicated in the pathophysiology of
schizophrenia. We administered subanesthetic doses of the NMDA receptor antagonist …
schizophrenia. We administered subanesthetic doses of the NMDA receptor antagonist …
Gender differences in the motivational processing of facial beauty
Gender may be involved in the motivational processing of facial beauty. This study applied
a behavioral probe, known to activate brain motivational regions, to healthy heterosexual …
a behavioral probe, known to activate brain motivational regions, to healthy heterosexual …
Psychological processing in chronic pain: a neural systems approach
LE Simons, I Elman, D Borsook - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Our understanding of chronic pain involves complex brain circuits that include sensory,
emotional, cognitive and interoceptive processing. The feed-forward interactions between …
emotional, cognitive and interoceptive processing. The feed-forward interactions between …
Alterations in brain structure and functional connectivity in prescription opioid-dependent patients
A dramatic increase in the use and dependence of prescription opioids has occurred within
the last 10 years. The consequences of long-term prescription opioid use and dependence …
the last 10 years. The consequences of long-term prescription opioid use and dependence …
The missing p in psychiatric training: why it is important to teach pain to psychiatrists
I Elman, JK Zubieta, D Borsook - Archives of general psychiatry, 2011 - jamanetwork.com
Context Pain problems are exceedingly prevalent among psychiatric patients. Moreover,
clinical impressions and neurobiological research suggest that physical and psychological …
clinical impressions and neurobiological research suggest that physical and psychological …
[HTML][HTML] Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation …
I Elman, D Borsook, SE Lukas - Neuropsychopharmacology, 2006 - nature.com
Obesity is highly prevalent among patients with schizophrenia and is associated with
detrimental health consequences. Although excessive consumption of fast food and …
detrimental health consequences. Although excessive consumption of fast food and …
Pain and analgesia: the value of salience circuits
D Borsook, R Edwards, I Elman, L Becerra… - Progress in …, 2013 - Elsevier
Evaluating external and internal stimuli is critical to survival. Potentially tissue-damaging
conditions generate sensory experiences that the organism must respond to in an appropriate, …
conditions generate sensory experiences that the organism must respond to in an appropriate, …