In the closing half of the past century a wide variety of approaches were developed to
visualise infection and inflammation by gamma scintigraphy. Use of autologous leucocytes, …

Interleukin 8 (IL-8) is a chemotactic cytokine that binds with a high affinity to receptors
expressed on neutrophils. Previous studies with various animal models showed that 99m Tc-…

At present there is considerable interest in labeling peptides with Tc-99m for the development
of target specific radiopharmaceuticals for imaging purposes. In the present study the …

Interleukin-8 (IL-8) is a chemotactic cytokine involved in activation and recruitment of neutrophils
to areas of infection. In our previous studies in rabbits we tested 123 I-labeled IL-8 for its …

Radiolabeled autologous leukocytes (WBCs) are the gold standard for imaging inflammatory
bowel disease (IBD). For the rapid and adequate management of patients with IBD, there is …

In our previous studies, interleukin-8 (IL-8) was labeled with 99m Tc using hydrazinonicotinamide
(HYNIC) as bifunctional coupling agent and tricine as coligand. This preparation …

Early and accurate diagnosis of osteomyelitis remains a clinical problem. Acute osteomyelitis
often occurs in infants and most often is located in the long bones. Radiologic images …

Nuclear medicine offers ideal techniques to visualize inflammatory processes using noninvasive
methods of whole-body scanning, enabling the determination of both the localization …

The cytokine interleukin-8 (IL-8) binds with high affinity to the CXCR1 and CXCR2 receptors
on neutrophils. In previous studies, we showed that 99m Tc-IL-8 could rapidly and …

Several radiolabeled chemotactic peptides have been tested for their suitability to show
infection and inflammation. Leukotriene B 4 (LTB 4 ) receptor-binding ligands could be useful …