Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation …

HE Wang, HM Yu, RS Liu, M Lin… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The ability to monitor tumor responses during prodrug activation gene therapy and other
anticancer gene therapies is critical for their translation into clinical practice. Previously, we …

Internal radiotherapy and dosimetric study for 111In/177Lu-pegylated liposomes conjugates in tumor-bearing mice

HE Wang, HM Yu, YC Lu, NN Heish, YL Tseng… - Nuclear Instruments and …, 2006 - Elsevier
In vivo characterization and dosimetric analysis has been performed to evaluate the
potential of pegylated liposomes as carriers of radionuclides in tumor internal radiotherapy. …

68Ga-labelled NOTA-RGD-GE11 peptide for dual integrin and EGFR-targeted tumour imaging

…, CH Tseng, PY Wang, CY Chien, HM Yu… - Nuclear Medicine and …, 2019 - Elsevier
Introduction Multiple peptide receptors are co-expressed in many types of cancers. Arg-Gly-Asp
(RGD) and GE11 peptides specifically target integrin α V β 3 and EGFR, respectively. …

Synthesis of 68Ga‐labeled NOTA‐RGD‐GE11 heterodimeric peptide for dual integrin and epidermal growth factor receptor‐targeted tumor imaging

HM Yu, JH Chen, KL Lin, WJ Lin - Journal of Labelled …, 2015 - Wiley Online Library
Radiolabeled Arg‐Gly‐Asp (RGD) peptide analogs have been extensively studied for α v β
3 integrin‐targeted angiogenesis imaging. According to recently presented evidence, the …

Development of single vial kits for preparation of 68Ga‐labelled hexavalent lactoside for PET imaging of asialoglycoprotein receptor

HM Yu, CH Chan, JH Chen, CY Chien… - Journal of Labelled …, 2018 - Wiley Online Library
The aim of this study was to formulate and evaluate the freeze‐dried kit of NOTA‐hexavalent
lactoside (NOTA‐HL) for the preparation of 68 Ga‐labeled glycoligand for PET imaging of …

Hexavalent lactoside labeled with [18F] AlF for PET imaging of asialoglycoprotein receptor

HM Yu, CH Chan, CH Yang, HT Hsia… - Applied Radiation and …, 2020 - Elsevier
Several methods have been developed to label compounds with 18 F. However, in general
these are laborious and require a multistep synthesis. A method based on the chelation of 18 …

The specificity and accuracy of 111In-hexavalent lactoside in estimating liver reserve and its threshold value for mortality in mice

MH Wang, CY Chien, PY Wang, HM Yu, HS Lee… - Journal of …, 2015 - Elsevier
Background & Aims The asialoglycoprotein receptor on hepatocyte membranes recognizes
the galactose residues of glycoproteins. We investigated the specificity, accuracy and …

Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-κB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on …

…, HC Wu, SJ Kao, FW Tseng, YS Wang, HM Yu… - Biochemical …, 2005 - Elsevier
The inhibition of thymidylate synthase (TS) by 5-fluorouracil (5-FU) was known to increase
the incorporation of radiolabelled iododeoxyuridine (IdUrd) into DNA. The relatively non-toxic …

[PDF][PDF] Investigation of polymer BANG gel dosimetry using X-ray computed tomographic imaging

SL Dong, TC Chu, HM Yu, YS Wu, YH Yeh… - Journal of Medical …, 2005 - researchgate.net
The purpose of this work is to determine the optimal X-ray computed tomography (CT) imaging
parameter settings for polymer BANG gel dosimetry. Several homemade polymer BANG …

Use of 111In-Hexavalent Lactoside for Liver Reserve Estimation in Rodents with Thioacetamide-Induced Hepatic Fibrosis

MH Wang, CY Chien, HM Yu, PY Wang… - Molecular …, 2018 - ACS Publications
Many biochemical tests detecting the presence of liver disease are not liver-specific and
may be abnormal in nonhepatic conditions. The asialoglycoprotein receptor (ASGPR) is a …