[HTML][HTML] PD-L1 is upregulated by EBV-driven LMP1 through NF-κB pathway and correlates with poor prognosis in natural killer/T-cell lymphoma

…, W Zhang, J Wang, W Liu, Z Xia, H Huang… - Journal of hematology & …, 2016 - Springer
Background Natural killer/T-cell lymphoma (NKTCL) is an Epstein–Barr virus (EBV)-associated,
highly aggressive lymphoma. Treatment outcome remains sub-optimal, especially for …

[HTML][HTML] Blood lymphocyte-to-monocyte ratio identifies high-risk patients in diffuse large B-cell lymphoma treated with R-CHOP

ZM Li, JJ Huang, Y Xia, J Sun, Y Huang, Y Wang… - PloS one, 2012 - journals.plos.org
Background Recent research has shown a correlation between immune microenvironment
and lymphoma biology. This study aims to investigate the prognostic significance of the …

Apatinib combined with oral etoposide in patients with platinum-resistant or platinum-refractory ovarian cancer (AEROC): a phase 2, single-arm, prospective study

…, YL Feng, Q Liu, HQ Huang, X Huang - The Lancet …, 2018 - thelancet.com
Background Anti-angiogenic therapy combined with chemotherapy could improve the
outcomes of patients with platinum-resistant ovarian cancer. Apatinib is an oral tyrosine kinase …

High incidence of hepatitis B virus infection in B‐cell subtype non‐Hodgkin lymphoma compared with other cancers

…, Y Shi, H Luo, W Jiang, T Lin, H Huang… - … Journal of the …, 2007 - Wiley Online Library
BACKGROUND. The authors investigated the prevalence of hepatitis B virus (HBV) infection
by using serologic markers in non‐Hodgkin lymphoma (NHL) compared with other types of …

[HTML][HTML] Locoregional radiotherapy in patients with distant metastases of nasopharyngeal carcinoma at diagnosis

…, Q Liu, R Sun, F Qiu, ZJ Xia, HQ Huang… - Chinese journal of …, 2013 - ncbi.nlm.nih.gov
Systemic chemotherapy is the basic palliative treatment for metastatic nasopharyngeal
carcinoma (NPC); however, it is not known whether locoregional radiotherapy targeting the …

[HTML][HTML] Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

…, B Li, XJ Xia, Y Xia, Y Laurensia, BKH Chia, HQ Huang… - Leukemia, 2019 - nature.com
Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy
strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in …

CD38 expression predicts poor prognosis and might be a potential therapy target in extranodal NK/T cell lymphoma, nasal type

L Wang, H Wang, P Li, Y Lu, Z Xia, H Huang… - Annals of …, 2015 - Springer
No standard chemotherapy regimens have been defined yet for extranodal natural killer/T
cell lymphoma (ENKTL), and the prognosis of patients with advanced or relapsed disease is …

[HTML][HTML] Myeloid-derived suppressor cells inhibit T cell proliferation in human extranodal NK/T cell lymphoma: a novel prognostic indicator

…, SB Ye, LY Ouyang, YS Chen, J He, HQ Huang… - Cancer Immunology …, 2015 - Springer
The expansion of myeloid-derived suppressor cells (MDSCs) and its correlation with advanced
disease stage have been shown in solid cancers. Here, we investigated the functional …

Lamivudine prophylaxis reduces the incidence and severity of hepatitis in hepatitis B virus carriers who receive chemotherapy for lymphoma

…, L Zhang, ZJ Xia, XF Sun, HQ Huang… - … Journal of the …, 2006 - Wiley Online Library
BACKGROUND Hepatitis B virus (HBV) infection is a common disease in China. Severe
hepatitis is a well recognized complication in HBV carriers with malignant disease who receive …

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations

GW Lin, C Xu, K Chen, HQ Huang, J Chen… - The Lancet …, 2020 - thelancet.com
Background Extranodal natural killer T-cell lymphoma (NKTCL; nasal type) is an aggressive
malignancy with a particularly high prevalence in Asian and Latin American populations. …