Salicylic acid‐inducible binding of a tobacco nuclear protein to a 10 bp sequence which is highly conserved amongst stress‐inducible genes

AP Goldsbrough, H Albrecht, R Stratford - The Plant Journal, 1993 - Wiley Online Library
A 10 bp sequence motif (TCATCTTCTT) which is repeated several times in the 5′ non‐transcribed
region of a barley β‐1,3‐glucanase gene is also present in the non‐translated …

Dynamic force spectroscopy of parallel individual Mucin1–antibody bonds

…, K Langry, EY Lau, H Albrecht… - Proceedings of the …, 2005 - National Acad Sciences
We used atomic force microscopy to measure the binding forces between Mucin1 (MUC1)
peptide and a single-chain variable fragment (scFv) antibody selected from a scFv library …

Flavonoids Promote Haustoria Formation in the Root ParasiteTriphysaria versicolor

H Albrecht, JI Yoder, DA Phillips - Plant Physiology, 1999 - academic.oup.com
Parasitic plants in the Scrophulariaceae develop infective root structures called haustoria in
response to chemical signals released from host-plant roots. This study used a simple in …

Production of soluble ScFvs with C-terminal-free thiol for site-specific conjugation or stable dimeric ScFvs on demand

H Albrecht, PA Burke, A Natarajan, CY Xiong… - Bioconjugate …, 2004 - ACS Publications
ScFv recombinant antibody fragments can provide specific tumor binding modules for
targeting drugs. In the process of building multimeric tumor targeting pharmaceuticals, a …

Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals

A Natarajan, CY Xiong, H Albrecht… - Bioconjugate …, 2005 - ACS Publications
New radiopharmaceuticals are possible using site-specific conjugation of small tumor binding
proteins and poly(ethylene glycol) (PEG) scaffolds to provide modular multivalent, homo- …

Monospecific bivalent scFv-SH: effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility

H Albrecht, GL DeNardo, SJ DeNardo - Journal of immunological methods, 2006 - Elsevier
Development of tumor targeting pharmaceuticals on a modular platform is an attractive
paradigm. Design choices for bispecific (anti-tumor and anti-chelate) pretargeting molecules are …

MUC1 and MUC4: switching the emphasis from large to small

H Albrecht, KL Carraway III - Cancer biotherapy & …, 2011 - liebertpub.com
Summation The MUC1 and MUC4 membrane mucins are each composed of a large alpha (α)
and a small beta (β) subunit. The α subunits are fully exposed at the cell surface and …

111In-LLP2A-DOTA polyethylene glycol–targeting α4β1 integrin: comparative pharmacokinetics for imaging and therapy of lymphoid malignancies

SJ DeNardo, R Liu, H Albrecht… - Journal of Nuclear …, 2009 - Soc Nuclear Med
N-[[4-[[[(2-ethylphenyl)amino]carbonyl]amino]phenyl]acetyl]-N ε -6-[(2E)-1-oxo-3-(3-pyridinyl-2-propenyl)]-l-lysyl-l-2-aminohexanedioyl-(1-amino-1-cyclohexane)carboxamide
(LLP2A) is …

Selective high-affinity ligand antibody mimics for cancer diagnosis and therapy: initial application to lymphoma/leukemia

…, A Natarajan, M Corzett, SJ DeNardo, H Albrecht… - Clinical cancer …, 2007 - AACR
Purpose: More than two decades of research and clinical trials have shown radioimmunotherapy
to be a promising approach for treating various forms of cancer. Lym-1 antibody, which …

The beta 2 adrenergic receptor antagonist timolol improves healing of combined burn and radiation wounds

H Albrecht, H Yang, M Kiuru… - Radiation …, 2018 - meridian.allenpress.com
In a scenario involving a nuclear detonation during war or a terrorist attack, acute radiation
exposure combined with thermal and blast effects results in severe skin injury. Although the …