User profiles for Hong Zhu

Hong Zhu

- Verified email at hms.harvard.edu - Cited by 19714

Hong-Jian Zhu

- Verified email at unimelb.edu.au - Cited by 10330

Hong Zhu

- Verified email at brookes.ac.uk - Cited by 6169

[HTML][HTML] Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China

H Su, M Yang, C Wan, LX Yi, F Tang, HY Zhu, F Yi… - Kidney international, 2020 - Elsevier
Although the respiratory and immune systems are the major targets of Coronavirus Disease
2019 (COVID-19), acute kidney injury and proteinuria have also been observed. Currently, …

Hyper-parameter optimization: A review of algorithms and applications

T Yu, H Zhu - arXiv preprint arXiv:2003.05689, 2020 - arxiv.org
Since deep neural networks were developed, they have made huge contributions to everyday
lives. Machine learning provides more rational advice than humans are capable of in …

[HTML][HTML] Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

H Li, H Zhu, C Xu, J Yuan - Cell, 1998 - cell.com
We report here that BID, a BH3 domain–containing proapoptotic Bcl2 family member, is a
specific proximal substrate of Casp8 in the Fas apoptotic signaling pathway. While full-length …

[HTML][HTML] Game consumption and the 2019 novel coronavirus

…, X Xie, X Cai, J Huang, X Tian, H Zhu - The Lancet Infectious …, 2020 - thelancet.com
In December, 2019, the 2019 novel coronavirus (2019 nCoV) infecting humans was first
identified in Wuhan, China. 1–3 As of Feb 3, 2020, the National Health Commission of China …

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

T Nakagawa, H Zhu, N Morishima, E Li, J Xu… - Nature, 2000 - nature.com
Apoptosis, or cellular suicide, is important for normal development and tissue homeostasis,
but too much or too little apoptosis can also cause disease 1 , 2 . The family of cysteine …

[HTML][HTML] Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults

E Selvin, MW Steffes, H Zhu, K Matsushita… - … England Journal of …, 2010 - Mass Medical Soc
Background Fasting glucose is the standard measure used to diagnose diabetes in the United
States. Recently, glycated hemoglobin was also recommended for this purpose. Methods …

Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3

M Miura, H Zhu, R Rotello, EA Hartwieg, J Yuan - Cell, 1993 - cell.com
The mammalian interleukin-lfl-converting enzyme (ICE) has sequence similarity to the C.
elegans cell death gene ted-3. We show here that overexpression of the murine ICE (mlCE) …

Software unit test coverage and adequacy

H Zhu, PAV Hall, JHR May - Acm computing surveys (csur), 1997 - dl.acm.org
Objective measurement of test quality is one of the key issues in software testing. It has been
a major research focus for the last two decades. Many test criteria have been proposed and …

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

…, E Hogg, D Welch, L Manness, C Lin, J Yu, H Zhu… - Nature medicine, 2003 - nature.com
Amyloid-β peptide (Aβ) interacts with the vasculature to influence Aβ levels in the brain and
cerebral blood flow, providing a means of amplifying the Aβ-induced cellular stress …

[HTML][HTML] Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α

…, M Lou, TC Elleman, TE Adams, GO Lovrecz, HJ Zhu… - Cell, 2002 - cell.com
We report the crystal structure, at 2.5 Å resolution, of a truncated human EGFR ectodomain
bound to TGFα. TGFα interacts with both L1 and L2 domains of EGFR, making many main …