Human ferritin cages for imaging vascular macrophages
M Terashima, M Uchida, H Kosuge, PS Tsao… - Biomaterials, 2011 - Elsevier
Atherosclerosis is a leading cause of death worldwide. Macrophages are key components
of vascular inflammation, which contributes to the development and complications of …
of vascular inflammation, which contributes to the development and complications of …
Protein cage nanoparticles bearing the LyP-1 peptide for enhanced imaging of macrophage-rich vascular lesions
M Uchida, H Kosuge, M Terashima, DA Willits… - ACS …, 2011 - ACS Publications
Cage-like protein nanoparticles are promising platforms for cell- and tissue-specific targeted
delivery of imaging and therapeutic agents. Here, we have successfully modified the 12 nm …
delivery of imaging and therapeutic agents. Here, we have successfully modified the 12 nm …
Near infrared imaging and photothermal ablation of vascular inflammation using single‐walled carbon nanotubes
H Kosuge, SP Sherlock, T Kitagawa… - Journal of the …, 2012 - Am Heart Assoc
Background Macrophages are critical contributors to atherosclerosis. Single‐walled carbon
nanotubes ( SWNT s) show promising properties for cellular imaging and thermal therapy, …
nanotubes ( SWNT s) show promising properties for cellular imaging and thermal therapy, …
Blockade of the interaction between PD-1 and PD-L1 accelerates graft arterial disease in cardiac allografts
N Koga, J Suzuki, H Kosuge, G Haraguchi… - … , and vascular biology, 2004 - Am Heart Assoc
Background— Programmed death-1 (PD-1), a member of the CD28 family, has been identified.
PD-1 is involved in the negative regulation of some immune responses. We evaluated …
PD-1 is involved in the negative regulation of some immune responses. We evaluated …
JCS 2017 guideline on management of vasculitis syndrome―digest version―
…, T Kawakami, R Kinouchi, A Kurata, H Kosuge… - Circulation …, 2020 - jstage.jst.go.jp
Vasculitis is a general term for diseases that cause inflammation in the blood vessels
themselves. Table 1 shows the 2012 revised version of Chapel Hill Consensus Conference (CHCC…
themselves. Table 1 shows the 2012 revised version of Chapel Hill Consensus Conference (CHCC…
Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines
…, S Mizuno, N Koga, S Adachi, H Kosuge… - Circulation …, 2005 - Am Heart Assoc
Hepatocyte growth factor (HGF) plays a role in cell protection, antiapoptosis, antifibrosis,
and angiogenesis. However, the role of HGF in the immune system is not well defined. We …
and angiogenesis. However, the role of HGF in the immune system is not well defined. We …
Ultraselective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques
Disruption of vulnerable atherosclerotic plaques often leads to myocardial infarction and
stroke, the leading causes of morbidity and mortality in the United States. A diagnostic method …
stroke, the leading causes of morbidity and mortality in the United States. A diagnostic method …
[HTML][HTML] Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma
…, H Okada, G Haraguchi, Y Onai, H Kosuge… - Laboratory …, 2011 - Elsevier
Unfavorable left ventricular (LV) remodeling after myocardial infarction (MI) leads to cardiac
dysfunction. We examined whether Telmisartan, an angiotensin (Ang) II type I receptor …
dysfunction. We examined whether Telmisartan, an angiotensin (Ang) II type I receptor …
[HTML][HTML] Expert consensus on the clinical use of pulse wave velocity in Asia
Arterial stiffness is a progressive aging process that predicts cardiovascular disease. Pulse
wave velocity (PWV) has emerged as a noninvasive, valid, and reliable measure of arterial …
wave velocity (PWV) has emerged as a noninvasive, valid, and reliable measure of arterial …
Characterizing cathepsin activity and macrophage subtypes in excised human carotid plaques
I Abd-Elrahman, K Meir, H Kosuge, Y Ben-Nun… - Stroke, 2016 - Am Heart Assoc
Background and Purpose— Atherosclerosis is a leading cause of mortality worldwide,
contributing to both strokes and heart attacks. Macrophages are key players in atherogenesis, …
contributing to both strokes and heart attacks. Macrophages are key players in atherogenesis, …