User profiles for Hiroshi Otani
 | Hiroshi OtaniDOE Joint Genome Institute, Lawrence Berkeley National Laboratory Verified email at lbl.gov Cited by 753 |
Host-selective toxins produced by the plant pathogenic fungus Alternaria alternata
…, M Egusa, M Yamamoto, H Otani - FEMS microbiology …, 2013 - academic.oup.com
Host-selective toxins (HSTs) produced by fungal plant pathogens are generally low-molecular-weight
secondary metabolites with a diverse range of structures that function as effectors …
secondary metabolites with a diverse range of structures that function as effectors …
Breaking Down Lignin to High-Value Chemicals: The Conversion of Lignocellulose to Vanillin in a Gene Deletion Mutant of Rhodococcus jostii RHA1
…, EM Hardiman, M Ahmad, H Otani… - ACS Chemical …, 2013 - ACS Publications
The aromatic polymer lignin represents a possible renewable source of aromatic chemicals,
if biocatalytic routes for lignin breakdown can be developed. The availability of a genome …
if biocatalytic routes for lignin breakdown can be developed. The availability of a genome …
Effect of reduced-dose vs high-dose glucocorticoids added to rituximab on remission induction in ANCA-associated vasculitis: a randomized clinical trial
…, Y Takakuwa, Y Makino, R Yoshimi, T Hayashi, H Otani… - Jama, 2021 - jamanetwork.com
Importance The current standard induction therapy for antineutrophil cytoplasm antibody (ANCA)–associated
vasculitis is the combination of high-dose glucocorticoids and …
vasculitis is the combination of high-dose glucocorticoids and …
Horizontal chromosome transfer, a mechanism for the evolution and differentiation of a plant-pathogenic fungus
Y Akagi, H Akamatsu, H Otani, M Kodama - Eukaryotic cell, 2009 - Am Soc Microbiol
The tomato pathotype of Alternaria alternata produces host-specific AAL toxin and causes
Alternaria stem canker on tomato. A polyketide synthetase (PKS) gene, ALT1, which is …
Alternaria stem canker on tomato. A polyketide synthetase (PKS) gene, ALT1, which is …
Molecular karyotypes for Alternaria plant pathogens known to produce host-specific toxins
H Akamatsu, M Taga, M Kodama, R Johnson, H Otani… - Current genetics, 1999 - Springer
There are at least ten plant diseases caused by Alternaria species in which host-specific
toxins (HSTs) are responsible for fungal pathogenicity. Of these HST-producers, seven are …
toxins (HSTs) are responsible for fungal pathogenicity. Of these HST-producers, seven are …
Spontaneous loss of a conditionally dispensable chromosome from the Alternaria alternata apple pathotype leads to loss of toxin production and pathogenicity
…, RD Johnson, H Akamatsu, A Salamiah, H Otani… - Current genetics, 2001 - Springer
The Alternaria alternata apple pathotype causes Alternaria blotch of susceptible apple
cultivars through the production of a cyclic peptide, host-specific toxin, AM-toxin. We recently …
cultivars through the production of a cyclic peptide, host-specific toxin, AM-toxin. We recently …
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria
It is generally believed that exchange of secondary metabolite biosynthetic gene clusters (BGCs)
among closely related bacteria is an important driver of BGC evolution and …
among closely related bacteria is an important driver of BGC evolution and …
Isolation and structures of AK-toxin I and II, host-specific phytotoxic metabolites produced by Alternaria alternata Japanese pear pathotype
…, T Taga, H Masuda, K Osaki, H Otani… - Agricultural and …, 1985 - jstage.jst.go.jp
AK-to x in T 4 13. 18 5 3 C 23 H 27O 6N 1.6 2 M+ 2 0 4. 10 2 1 C 12 H 14O 2N-0. 2 3 4(A) 17
6. 10 7 7 C n H 14O N 0.3 5 5(B) 13 4. 09 41 C 9H 12N-2.7 5 4(C) 10 5. 06 78 C, H 9-2.5 10 …
6. 10 7 7 C n H 14O N 0.3 5 5(B) 13 4. 09 41 C 9H 12N-2.7 5 4(C) 10 5. 06 78 C, H 9-2.5 10 …
Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction
I Shimokawa, Y Higami, T Tsuchiya, H Otani… - The FASEB …, 2003 - Wiley Online Library
A reduced growth hormone (GH)‐insulin‐like growth factor (IGF)‐1 axis is associated with
an extension of lifespan in laboratory rodents. Several phenotypes of such animal models …
an extension of lifespan in laboratory rodents. Several phenotypes of such animal models …
[HTML][HTML] Comparative and pangenomic analysis of the genus Streptomyces
Streptomycetes are highly metabolically gifted bacteria with the abilities to produce bioproducts
that have profound economic and societal importance. These bioproducts are produced …
that have profound economic and societal importance. These bioproducts are produced …