User profiles for Hironobu Fujiwara

Hironobu Fujiwara

Team Leader of RIKEN Center for Developmental Biology
Verified email at cdb.riken.jp
Cited by 2188

Cell-extracellular matrix interactions in normal and diseased skin

FM Watt, H Fujiwara - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Mammalian skin comprises a multi-layered epithelium, the epidermis, and an underlying
connective tissue, the dermis. The epidermal extracellular matrix is a basement membrane, …

Tracing the origin of hair follicle stem cells

…, T Abe, H Kiyonari, Y Furuta, I Nikaido, H Fujiwara - Nature, 2021 - nature.com
Tissue stem cells are generated from a population of embryonic progenitors through organ-specific
morphogenetic events 1 , 2 . Although tissue stem cells are central to organ …

[HTML][HTML] The basement membrane of hair follicle stem cells is a muscle cell niche

H Fujiwara, M Ferreira, G Donati, DK Marciano… - Cell, 2011 - cell.com
The hair follicle bulge in the epidermis associates with the arrector pili muscle (APM) that is
responsible for piloerection ("goosebumps"). We show that stem cells in the bulge deposit …

[HTML][HTML] Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions

…, R Morita, K Sekiguchi, JH Miner, H Fujiwara - Nature …, 2021 - nature.com
Inter-tissue interaction is fundamental to multicellularity. Although the basement membrane (BM)
is located at tissue interfaces, its mode of action in inter-tissue interactions remains …

Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by α3β1, α6β1 and α6β4 integrins

Y Kikkawa, N Sanzen, H Fujiwara… - Journal of cell …, 2000 - journals.biologists.com
Laminin-10/11, the laminin isoforms containing the α5 chain, are major components of
basement membranes of many fetal and adult tissues. Laminin-10/11 purified from the …

Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors

…, K Natsuga, R Sinclair, H Fujiwara… - Proceedings of the …, 2014 - National Acad Sciences
It has long been recognized that the hair follicle growth cycle and oscillation in the thickness
of the underlying adipocyte layer are synchronized. Although factors secreted by adipocytes …

[HTML][HTML] Purification and Characterization of Human Laminin-8: Laminin-8 stimulates cell adhesion and migration through α3β1 AND α6β1integrins

H Fujiwara, Y Kikkawa, N Sanzen… - Journal of Biological …, 2001 - ASBMB
Recently identified laminin isoforms containing the α4 chain have been shown to be
expressed in the basement membrane of restricted organs such as heart, skeletal muscle, and …

Atmospheric anomalies observed during earthquake occurrences

H Fujiwara, M Kamogawa, M Ikeda… - Geophysical …, 2004 - Wiley Online Library
Appearance of anomalies in the atmosphere before earthquakes (EQs) has been verified,
through observation of anomalous transmission of VHF electromagnetic (EM) waves beyond …

Anterior cingulate pathology and social cognition in schizophrenia: a study of gray matter, white matter and sulcal morphometry

H Fujiwara, K Hirao, C Namiki, M Yamada, M Shimizu… - Neuroimage, 2007 - Elsevier
The anterior cingulate gyrus (ACG) is a critical structure for social cognitive processing; the
pathology of this structure might be a major source of social dysfunction in schizophrenia. …

Anterior and posterior cingulum abnormalities and their association with psychopathology in schizophrenia: a diffusion tensor imaging study

H Fujiwara, C Namiki, K Hirao, J Miyata, M Shimizu… - Schizophrenia …, 2007 - Elsevier
Evidence suggests that a disruption in limbic system network integrity and, in particular, the
cingulate gyrus may play a role in the pathophysiology of schizophrenia. The cingulum …