Cardiac fibrosis, defined as a proliferation of interstitial fibroblasts and biosynthesis of
extracellular matrix components in the ventricles of the heart, is a consequence of remodeling …

ras genes encode members of the small GTP-binding proteins. Ras protein is highly conserved
in various species from yeast to humans and plays a key role in signal transduction. Ras …

The Rac1, a member of the Rho family proteins, regulates actin organization of cytoskeleton
and cell adhesion. We used genetic analysis to elucidate the role of Rac1 in mouse …

Objectives : We examined whether right ventricular (RV) [ 18 F]fluorodeoxyglucose (FDG)
accumulation is increased in patients with pulmonary hypertension using gated positron …

Backgrounds A mouse receptor tyrosine kinase (RTK), mRor2, which belongs to the Ror‐family
of RTKs consisting of at least two structurally related members, is primarily expressed in …

KiSS‐1 is a promising candidate tumor‐suppressor gene and may play a key role in the
metastatic cascade. The expression profile and the role of KiSS‐1 in cancer progression are …

OBJECTIVE. Real-time maximum dose monitoring of the skin is unavailable on many of the
X-ray machines that are used for cardiac intervention procedures. Therefore, some reports …

Signaling through the Ror2 receptor tyrosine kinase promotes invadopodia formation for
tumor invasion. Here, we identify intraflagellar transport 20 (IFT20) as a new target of this …

Backgrounds Drosophila neurospecific receptor tyrosine kinases (RTKs), Dror and Dnrk, as
well as Ror1 and Ror2 RTKs, isolated from human neuroblastoma, have been identified as a …

OBJECTIVE. The objective of our study was to use MRI to analyze the topographic
localization of myocardial lesions and their relationship to plasma brain natriuretic peptide (BNP) …