Radiosynthesis, photoisomerization, biodistribution, and metabolite analysis of 11C-PBB3 as a clinically useful PET probe for imaging of tau pathology
H Hashimoto, K Kawamura, N Igarashi… - Journal of Nuclear …, 2014 - Soc Nuclear Med
2-((1E,3E)-4-(6-( 11 C-methylamino)pyridin-3-yl)buta-1,3-dienyl)benzo[d]thiazol-6-ol ( 11 C-PBB3)
is a clinically useful PET probe that we developed for in vivo imaging of tau pathology …
is a clinically useful PET probe that we developed for in vivo imaging of tau pathology …
Preparation of chitosan hydrogel and its solubility in organic acids
T Furuike, D Komoto, H Hashimoto… - International journal of …, 2017 - Elsevier
The increase of the stability of chitosan (CS) in the solution is extremely important for the
application of CS in various fields. In this study, we describe that the hydrogelation of CS can …
application of CS in various fields. In this study, we describe that the hydrogelation of CS can …
Surface characterization of imidazolium ionic liquids by high-resolution Rutherford backscattering spectroscopy and X-ray photoelectron spectroscopy
H Hashimoto, A Ohno, K Nakajima, M Suzuki, H Tsuji… - Surface Science, 2010 - Elsevier
The surface composition of 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM] [PF 6
]) and 1-butyl-3-methylimidazolium dicyanamide ([BMIM] [DCA]) are studied by high-…
]) and 1-butyl-3-methylimidazolium dicyanamide ([BMIM] [DCA]) are studied by high-…
Nectin-4: A novel therapeutic target for skin cancers
H Hashimoto, Y Tanaka, M Murata, T Ito - Current Treatment Options in …, 2022 - Springer
Opinion statement Nectin-4 is a tumor-associated antigen that is highly expressed on various
cancer cells, and it has been further proposed to have roles in tumor development and …
cancer cells, and it has been further proposed to have roles in tumor development and …
Dynamic changes in striatal mGluR1 but not mGluR5 during pathological progression of Parkinson's disease in human alpha-synuclein A53T transgenic rats: a multi …
…, S Shiomi, M Takei, H Hashimoto… - Journal of …, 2016 - Soc Neuroscience
Parkinson's disease (PD) is a prevalent degenerative disorder affecting the CNS that is primarily
characterized by resting tremor and movement deficits. Group I metabotropic glutamate …
characterized by resting tremor and movement deficits. Group I metabotropic glutamate …
Current management and treatment of extramammary Paget's disease
H Hashimoto, T Ito - Current Treatment Options in Oncology, 2022 - Springer
Opinion statement Extramammary Paget’s disease (EMPD) is a rare neoplastic disease
affecting areas rich in apocrine glands in the elderly. EMPD clinically resembles a benign …
affecting areas rich in apocrine glands in the elderly. EMPD clinically resembles a benign …
Observation of surface structure of 1-alkyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imide using high-resolution Rutherford backscattering spectroscopy
K Nakajima, A Ohno, H Hashimoto, M Suzuki… - The Journal of …, 2010 - pubs.aip.org
The surface structures of 1-alkyl-3-methylimidazolium bis (trifluoromethanesulfonyl) imide ([C
n MIM][TFSI], n= 2, 4, 6) are studied by high-resolution Rutherford backscattering …
n MIM][TFSI], n= 2, 4, 6) are studied by high-resolution Rutherford backscattering …
Identification of a major radiometabolite of [11C] PBB3
H Hashimoto, K Kawamura, M Takei, N Igarashi… - Nuclear medicine and …, 2015 - Elsevier
Introduction [ 11 C]PBB3 is a clinically used positron emission tomography (PET) probe for
in vivo imaging of tau pathology in the brain. Our previous study showed that [ 11 C]PBB3 …
in vivo imaging of tau pathology in the brain. Our previous study showed that [ 11 C]PBB3 …
[HTML][HTML] Trop2 expression in extramammary Paget's disease and normal skin
T Ito, K Tanegashima, Y Tanaka, H Hashimoto… - International journal of …, 2021 - mdpi.com
Extramammary Paget’s disease (EMPD) is a rare skin cancer arising in the apocrine gland-rich
areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor …
areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor …
[HTML][HTML] The outcome of chemotherapy for metastatic extramammary Paget's disease
H Hashimoto, Y Kaku-Ito, M Furue, T Ito - Journal of Clinical Medicine, 2021 - mdpi.com
The efficacy and survival impact of conventional chemotherapies for metastatic extramammary
Paget’s disease (EMPD) have not been fully elucidated. This study examined the long-…
Paget’s disease (EMPD) have not been fully elucidated. This study examined the long-…