Background Preclinical studies have established that implantation of bone marrow-mononuclear
cells, including endothelial progenitor cells, into ischaemic limbs increases collateral …

3. Morbidity and mortality rates due to diseases such as stroke, myocardial infarction, heart
disease and chronic renal disease increase with elevating blood pressure. The effects of …

Background Bone marrow implantation (BMI) was shown to enhance angiogenesis in a rat
ischemic heart model. This preclinical study using a swine model was designed to test the …

Since the discovery of nonpeptidic ligands, the receptors for angiotensin (Ang) II have been
classified into 2 subtypes (Ang II type 1 receptor [AT 1 -R] and Ang II type 2 receptor [AT 2 -R])…

Angiotensin II (Ang II) is a potent vasopressor peptide that interacts with 2 major receptor
isoforms — AT1 and AT2. Although blood pressure is increased in AT2 knockout mice, the …

Background— Increased production of reactive oxygen species (ROSs) by angiotensin II (Ang
II) is involved in the initiation and progression of cardiovascular diseases. NADPH …

Peripheral blood (PB)-derived CD14 + monocytes were shown to transdifferentiate into
endothelial cell (EC) lineage cells and contribute to neovascularization. We investigated whether …

Increasing evidence suggests that angiotensin II (AngII) acts as a modulator for ventricular
remodeling after myocardial infarction. Using competitive reverse-transcriptase polymerase …

Background— Peripheral blood mononuclear cells (PBMNCs), platelets, and polymorphonuclear
leukocytes (PMNs) contain various angiogenic factors and cytokines. Methods and …

BACKGROUND: Angiogenic cell therapy by intramuscular injection of autologous bone
marrow mononuclear cells was first attempted in patients with peripheral artery disease (PAD) …