Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential
Y Fujibayashi, H Taniuchi, Y Yonekura… - The Journal of …, 1997 - search.proquest.com
An ideal hypoxia imaging agent should have high membrane permeability for easy access
to intracellular mitochondria and low redox potential to confer stability in normal tissue, but it …
to intracellular mitochondria and low redox potential to confer stability in normal tissue, but it …
JTP-103237, a novel monoacylglycerol acyltransferase inhibitor, modulates fat absorption and prevents diet-induced obesity
…, H Tadaki, H Hamada, T Oda, H Taniuchi… - European Journal of …, 2015 - Elsevier
Monoacylglycerol acyltransferase 2 (MGAT2) plays an important role in intestinal fat
absorption. We discovered the novel MGAT2 inhibitor, JTP-103237, and evaluated its …
absorption. We discovered the novel MGAT2 inhibitor, JTP-103237, and evaluated its …
Mitochondria-selective reduction of 62Cu-pyruvaldehyde bis (N4-methylthiosemicarbazone)(62Cu-PTSM) in the murine brain; a novel radiopharmaceutical for brain …
Y Fujibayashi, K Wada, H Taniuchi… - Biological and …, 1993 - jstage.jst.go.jp
The retention mechanism of 62 Cu-pyruvaldehyde bis (N 4-methylthiosemicarbazone)(62
Cu-PTSM) in the murine brain was evaluated. For this purpose, stable Cu-PTSM was …
Cu-PTSM) in the murine brain was evaluated. For this purpose, stable Cu-PTSM was …
Differential mechanism of retention of Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (Cu-PTSM) by brain and tumor: A novel radiopharmaceutical for positron …
Y Fujibayashi, H Taniuchi, K Wada, Y Yonekura… - Annals of nuclear …, 1995 - Springer
The reductive retention of 62 Cu-PTSM was comparatively studied in the brain and Ehrlich
ascites tumor cells by electron spin resonance spectrometry and nonradioactive Cu-PTSM. In …
ascites tumor cells by electron spin resonance spectrometry and nonradioactive Cu-PTSM. In …
[PDF][PDF] Hyperfixation of copper-62-PTSM in rat brain after transient global ischemia
H Taniuchi, Y Fujibayashi, Y Yonekura… - Journal of Nuclear …, 1997 - Soc Nuclear Med
Results: Copper-62-PTSM showed accelerated accumulation in the brain at 1 hr and 1 day
after reperfusion when compared with that of 123I-IMP (p< 0.01), and this enhancement was …
after reperfusion when compared with that of 123I-IMP (p< 0.01), and this enhancement was …
Cu-pyruvaldehyde-bis (N4-methylthiosemicarbazone)(Cu-PTSM), a metal complex with selective NADH-dependent reduction by complex I in brain mitochondria: a …
H Taniuchi, Y Fujibayashi, H OKAZAWA… - Biological and …, 1995 - jstage.jst.go.jp
The reductive retention mechanism of copper (II)-pyruvaldehyde-bis (N 4-methylthiosemicarbazone)(Cu-PTSM),
a generator-produced positron-emitting 62 Cu-labeled …
a generator-produced positron-emitting 62 Cu-labeled …
Intracellular metabolism of 99mTc-d, l-HMPAO in vitro: a basic approach for understanding the hyperfixation mechanism in damaged brain
Y Fujibayashi, H Taniuchi, A Waki, A Yokoyama… - Nuclear medicine and …, 1998 - Elsevier
The mechanism of technetium-99m-labeled d,l-hexamethylpropylene amine oxime ( 99m Tc-HMPAO)
hyperfixation in damaged brain was elucidated using in vitro metabolic studies. …
hyperfixation in damaged brain was elucidated using in vitro metabolic studies. …
[HTML][HTML] JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis
…, H Tadaki, T Ishigure, S Sakata, H Taniuchi… - Journal of …, 2015 - Elsevier
Aim Monoacyglycerol acyltransferases (MGATs) are known to play important roles in intestinal
TG absorption. In contrast, the role of MGATs in the liver is still unclear. We investigated …
TG absorption. In contrast, the role of MGATs in the liver is still unclear. We investigated …
Effects of ischemia-reperfusion injury on myocardial single pass extraction and retention of Cu-PTSM in perfused rat hearts: Comparison with 201Tl and 14C …
K Wada, Y Fujibayashi, H Taniuchi, N Tajima… - Nuclear medicine and …, 1994 - Elsevier
The effects of ischemia-reperfusion-induced myocardial damage on the single pass
extraction and retention of 64 Cu-pyruvaldehyde-di-(N 4 -methylthiosemicabazone) ( 64 Cu-PTSM) …
extraction and retention of 64 Cu-pyruvaldehyde-di-(N 4 -methylthiosemicabazone) ( 64 Cu-PTSM) …
Development of glycoside-bound radiopharmaceuticals: novel radioiodination method for digoxin
…, Y FUJIBAYASHI, N DOTE, H TANIUCHI… - Biological and …, 1994 - jstage.jst.go.jp
We combined 2-hydroxy-3—methylbenzoylhydrazide (HMBH) with glycosides as a novel
method for the radioiodination of physiologically active glycosides. This method was tested …
method for the radioiodination of physiologically active glycosides. This method was tested …