Oral care reduces pneumonia in older patients in nursing homes

…, Y Akagawa, K Hashimoto, H Sasaki… - Journal of the …, 2002 - Wiley Online Library
OBJECTIVES: Aspiration of oral secretions and their bacteria is increasingly being recognized
as an important factor in pneumonia. We investigated whether oral care lowers the …

[PDF][PDF] Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema

…, K Sekizawa, S Shibahara, H Sasaki - The American Journal of …, 2000 - cell.com
Cigarette smoke, containing reactive oxygen species, is the most important risk factor for
chronic pulmonary emphysema (CPE). Heme oxygenase-1 (HO-1) plays a protective role as an …

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

T Aikawa, S Shimura, H Sasaki, M Ebina, T Takishima - Chest, 1992 - Elsevier
To examine the changes in airways in bronchial asthma (BA) during an asthma attack causing
death, we performed morphometric analysis of autopsied lungs from three outpatients …

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis

…, J Goto, MT Lotze, JK Kolls, H Sasaki - The Journal of …, 2005 - journals.aai.org
In this study, we examined the biological action of IL-17 on human non-small cell lung
cancer (NSCLC). Although IL-17 had no direct effect on the in vitro growth rate of NSCLC, IL-17 …

Oral care and pneumonia

T Yoneyama, M Yoshida, T Matsui, H Sasaki - The Lancet, 1999 - thelancet.com
D Simons and colleagues (May 22, p 1761) 1 report poor oral status of the institutionalised
elderly in the UK, which may contribute to the eating disorders and low nutrient and vitamin C …

Anticoagulant therapy for idiopathic pulmonary fibrosis

…, M Yanai, T Suzuki, M Yamaya, M Watanabe, H Sasaki - Chest, 2005 - Elsevier
… a , Nakayama Katsutoshi MD a , Yanai Masaru MD d , Suzuki Tomoko MD c , Yamaya
Mutsuo MD a , Watanabe Mika MD b , Sasaki Hidetada MD, PhD (Professor and Chairman) a …

High incidence of silent aspiration in elderly patients with community-acquired pneumonia.

…, T Konno, N Mishina, K Sekizawa, H Sasaki - American journal of …, 1994 - atsjournals.org
Pneumonia is a major cause of death in the elderly. To investigate the role of silent aspiration
in community-acquired pneumonia, we examined the occurrence of silent aspiration …

Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury

…, M Numasaki, S Ueda, T Suzuki, H Sasaki - The Journal of …, 2004 - journals.aai.org
Tissue repair often occurs in organs damaged by an inflammatory response. Inflammatory
stimuli induce a rapid and massive release of inflammatory cells including neutrophils from …

Site of airway obstruction in pulmonary disease: direct measurement of intrabronchial pressure

…, K Sekizawa, T Ohrui, H Sasaki… - Journal of Applied …, 1992 - journals.physiology.org
To partition the central and peripheral airway resistance in awake humans, a catheter-tipped
micromanometer sensing lateral pressure of the airway was wedged into the right lower …

Increased carbon monoxide in exhaled air of asthmatic patients

…, S Okinaga, M Yamaya, T Ohrui, H Sasaki - American Journal of …, 1997 - atsjournals.org
Exhaled carbon monoxide (CO) concentrations were measured on a CO monitor by vital
capacity maneuvers in asthmatic patients receiving or not receiving inhaled corticosteroids and …