Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations

MM Welling, A Paulusma-Annema, HS Balter… - European journal of …, 2000 - Springer
Original article Page 1 Abstract. The aim of this study was to select technetium-99m labelled
peptides that can discriminate between bacterial infections and sterile inflammations. For …

99mTc-labeled antimicrobial peptides for detection of bacterial and Candida albicans infections

…, A Lupetti, HS Balter, S Lanzzeri… - Journal of Nuclear …, 2001 - Soc Nuclear Med
This study compared the possibilities and limitations of 99m Tc-labeled synthetic peptides
derived from two human antimicrobial peptides, namely, ubiquicidin (UBI) and lactoferrin (hLF)…

Radiochemical and biological characteristics of 99mTc-UBI 29–41 for imaging of bacterial infections

MM Welling, S Mongera, A Lupetti, HS Balter… - Nuclear medicine and …, 2002 - Elsevier
A technetium-99m-labeled peptide derived from ubiquicidine, further referred to as 99m Tc-UBI
29–41, targets bacterial and fungal infections, but not sterile inflammatory processes, in …

Improved radioiodination of biomolecules using exhaustive Chloramine-T oxidation

AM Robles, HS Balter, P Oliver, MM Welling… - Nuclear medicine and …, 2001 - Elsevier
To improve standardization in analytical reagents we investigated Chloramine-T radioiodination
( 125 I) of several biomolecules based on the use of a single amount of the oxidizing …

Kit with technetium‐99m labelled antimicrobial peptide UBI 29‐41 for specific infection detection

…, P Oliver, R Mikolajczak, HS Balter… - Journal of Labelled …, 2005 - Wiley Online Library
The purpose of this study was to investigate radiochemical and biological characteristics of
an instant kit for the preparation of 99m Tc‐labelled UBI 29‐41 for specific detection of …

[PDF][PDF] Human pharmacokinetics and radiopharmacological studies of the myocardial perfusion agent: Technetium (2-carbomethoxy-2-isocyano-propane) 6+

…, AS Leòn, ES Verdera, HS Balter… - Journal of Nuclear …, 1992 - Soc Nuclear Med
99mTc@ pI preparations. The characteristic RP-HPLC retention times were used to identify
metabolites of the parent@ mTc@ CPI agent after exposure to biological samples. Synthesis …

In vitro and in vivo evaluation of [99mTc (CO) 3]-radiolabeled ErbB-2-targeting peptides for breast carcinoma imaging

…, O Alonso, TP Quinn, HS Balter… - Current …, 2010 - ingentaconnect.com
ErbB-2 is a type 1 receptor tyrosine kinase over-expressed on ~30% of breast cancers and
is an attractive target for the development of new diagnostic and therapeutic agents. In this …

In-site interaction evaluation of Tn density by inhibition/competition assays

A Robles, A Medeiros, N Berois, HS Balter… - Nuclear medicine and …, 2010 - Elsevier
The tumor-associated structure N-acetyl-galactosamine-O-Ser/Thr (Tn antigen), which is
overexpressed in various tumor cell types, notably of the breast, ovary and colon, is an …

Specificity of^ sup 99m^ Tc-Ciprofloxacin imaging/Reply

…, PH Nibbering, A Lupetti, HS Balter - The Journal of …, 2003 - search.proquest.com
TO THE EDITOR: We have read with interest the letters by Das et al.(1) and Pauwels et al.(2)
regarding the characteristics of^ sup 99m^ Tc-ciprofloxacin imaging for detection of …

Technetium-99m labeled cationic antimicrobial peptides for infection detection and treatment monitoring

EKJ Pauwels, MM Welling, HS Balter… - Drugs of the …, 2003 - access.portico.org
Small cationic peptides radiolabeled with technetium-99m are new tools for the scintigraphic
imaging of bacterial infections. Due to the specific binding of these peptides to the bacterial …