[PDF][PDF] Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment
…, AC DeCarvalho, S Lyu, P Li, Y Li, F Barthel, HJ Cho… - Cancer cell, 2017 - cell.com
We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
expression profiles to define three tumor-intrinsic transcriptional subtypes designated as …
[PDF][PDF] Spatiotemporal evolution of the primary glioblastoma genome
Tumor recurrence following treatment is the major cause of mortality for glioblastoma multiforme
(GBM) patients. Thus, insights on the evolutionary process at recurrence are critical for …
(GBM) patients. Thus, insights on the evolutionary process at recurrence are critical for …
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy
Outcomes of anticancer therapy vary dramatically among patients due to diverse genetic
and molecular backgrounds, highlighting extensive intertumoral heterogeneity. The …
and molecular backgrounds, highlighting extensive intertumoral heterogeneity. The …
Chemiresistive hydrogen sensors: fundamentals, recent advances, and challenges
Hydrogen (H 2 ) is one of the next-generation energy sources because it is abundant in nature
and has a high combustion efficiency that produces environmentally benign products (H 2 …
and has a high combustion efficiency that produces environmentally benign products (H 2 …
[PDF][PDF] Mutational landscape of secondary glioblastoma guides MET-targeted trial in brain tumor
Low-grade gliomas almost invariably progress into secondary glioblastoma (sGBM) with
limited therapeutic option and poorly understood mechanism. By studying the mutational …
limited therapeutic option and poorly understood mechanism. By studying the mutational …
[HTML][HTML] Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
JK Sa, N Chang, HW Lee, HJ Cho, M Ceccarelli… - Genome biology, 2020 - Springer
Background Glioblastoma (GBM) is a complex disease with extensive molecular and
transcriptional heterogeneity. GBM can be subcategorized into four distinct subtypes; tumors that …
transcriptional heterogeneity. GBM can be subcategorized into four distinct subtypes; tumors that …
Metal–Organic Framework Templated Catalysts: Dual Sensitization of PdO–ZnO Composite on Hollow SnO2 Nanotubes for Selective Acetone Sensors
Metal–organic framework (MOF)-derived synergistic catalysts were easily functionalized on
hollow SnO 2 nanotubes (NTs) via electrospinning and subsequent calcination. Nanoscale …
hollow SnO 2 nanotubes (NTs) via electrospinning and subsequent calcination. Nanoscale …
Determinants of response and intrinsic resistance to PD-1 blockade in microsatellite instability–high gastric cancer
This study highlights response heterogeneity within MSI-H gastric cancer treated with
pembrolizumab monotherapy and underscores the potential for extended baseline and early on-…
pembrolizumab monotherapy and underscores the potential for extended baseline and early on-…
Innovative nanosensor for disease diagnosis
Conspectus As a futuristic diagnosis platform, breath analysis is gaining much attention
because it is a noninvasive, simple, and low cost diagnostic method. Very promising clinical …
because it is a noninvasive, simple, and low cost diagnostic method. Very promising clinical …
Combined cooling, heating and power: A review of performance improvement and optimization
This paper presents a review on combined cooling, heating, and power (CCHP) systems.
This work summarizes the methods used to perform energetic and exergetic analyses, system …
This work summarizes the methods used to perform energetic and exergetic analyses, system …