[HTML][HTML] Circadian genes Per1 and Per2 increase radiosensitivity of glioma in vivo

…, F Zhou, H Shaocai, L Guangxing, X Hechun - Oncotarget, 2015 - ncbi.nlm.nih.gov
Per1 and Per2 play a key role in regulating the circadian rhythm in mammals. We report
here that although both genes were expressed with a circadian rhythm in glioma and normal …

[HTML][HTML] Intravenous transplantation of olfactory ensheathing cells reduces neuroinflammation after spinal cord injury via interleukin-1 receptor antagonist

…, TJ Grönroos, C Han, FR López-Picón, H Xia - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Olfactory ensheathing cell (OEC) transplantation has emerged as a promising
therapy for spinal cord injury (SCI) repair. In the present study, we explored the possible …

Deregulated expression of the clock genes in gliomas

…, W Liang, X Chen, Y Feng, H Xia… - … in cancer research …, 2013 - journals.sagepub.com
Growing evidence shows that the deregulation of the circadian clock plays an important role
in the development of malignant tumors, including gliomas. However, the molecular …

[HTML][HTML] PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β‑catenin signaling pathway

D Ma, L Hou, H Xia, H Li, H Fan, X Jia… - Oncology …, 2020 - spandidos-publications.com
Glioblastoma is a highly malignant tumor that contains stem‑like cells known as glioma stem
cells (GSCs), which lare associated with an increased risk of glioma occurrence, recurrence …

Intravenous transplantation of olfactory bulb ensheathing cells for a spinal cord hemisection injury rat model

L Zhang, X Zhuang, Y Chen, H Xia - Cell Transplantation, 2019 - journals.sagepub.com
Cellular transplantation strategies utilizing intraspinal or intrathecal olfactory ensheathing
cells (OECs) have been reported as beneficial for spinal cord injury (SCI). However, there are …

[HTML][HTML] Integration of BOLD-fMRI and DTI into radiation treatment planning for high-grade gliomas located near the primary motor cortexes and corticospinal tracts

M Wang, H Ma, X Wang, Y Guo, X Xia, H Xia, Y Guo… - Radiation …, 2015 - Springer
Background The main objective of this study was to evaluate the efficacy of integrating the
blood oxygen level dependent functional magnetic resonance imaging (BOLD-fMRI) and …

[HTML][HTML] Regulation of sleep disorders in patients with traumatic brain injury by intestinal flora based on the background of brain-gut axis

…, K Jing, B Jinbo, C Yanjun, X Hechun - Frontiers in …, 2022 - frontiersin.org
Objective This study investigates whether people with sleep disorders following traumatic
brain injury exhibit altered intestinal flora. The changes may allow us to gain a better …

[HTML][HTML] Integrated transcriptomic and metabolomic profiling reveals dysregulation of purine metabolism during the acute phase of spinal cord injury in rats

…, Y Chen, H Li, J Hui, L Zhang, X Hu, H Xia - Frontiers in …, 2022 - frontiersin.org
Introduction Spinal cord injury (SCI) results in drastic dysregulation of microenvironmental
metabolism during the acute phase, which greatly affects neural recovery. A better insight into …

[HTML][HTML] Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway

N Zhanfeng, W Chengquan, X Hechun, W Jun… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The Period2 (Per2) gene is an essential component of the mammalian circadian clock and
is strongly linked to glioma occurrence and its response to radiotherapy. Here, we examined …

[HTML][HTML] Lycium barbarum glycopeptide alleviates neuroinflammation in spinal cord injury via modulating docosahexaenoic acid to inhibiting MAPKs/NF-kB and …

…, J Hui, P Bie, Y Chen, H Liu, H Fan, H Xia - Journal of Translational …, 2023 - Springer
Background Lycium barbarum polysaccharide (LBP) is an active ingredient extracted from
Lycium barbarum that inhibits neuroinflammation, and Lycium barbarum glycopeptide (LbGp) …