[HTML][HTML] DCE-MRI assessment of response to neoadjuvant SABR in early stage breast cancer: Comparisons of single versus three fraction schemes and two different …

M Mouawad, H Biernaski, M Brackstone, M Lock… - Clinical and …, 2020 - Elsevier
Purpose To determine the effect of dose fractionation and time delay post-neoadjuvant
stereotactic ablative radiotherapy (SABR) on dynamic contrast-enhanced (DCE)-MRI parameters …

A noninvasive method for quantifying cerebral metabolic rate of oxygen by hybrid PET/MRI: validation in a porcine model

L Narciso, T Ssali, L Liu, H Biernaski… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The gold standard for imaging the cerebral metabolic rate of oxygen (CMRO 2 ) is PET;
however, it is an invasive and complex procedure that also requires correction for recirculating …

Functional CT assessment of extravascular contrast distribution volume and myocardial perfusion in acute myocardial infarction

…, A MacDonald, D Gaskin, J Butler, H Biernaski… - International Journal of …, 2018 - Elsevier
Purpose In a pig model of acute myocardial infarction (AMI), we validated a functional
computed tomography (CT) technique for concomitant assessment of myocardial edema and …

[HTML][HTML] Changes in myocardial blood flow in a canine model of left sided breast cancer radiotherapy

…, M Mouawad, JM Sykes, J Butler, H Biernaski… - Plos one, 2023 - journals.plos.org
Background Left-sided breast cancer patients receiving adjuvant radiotherapy are at risk for
coronary artery disease, and/or radiation mediated effects on the microvasculature. …

Heart Rate−Independent 3D Myocardial Blood Oxygen Level−Dependent MRI at 3.0 T with Simultaneous 13N−Ammonia PET Validation

HJ Yang, D Dey, J Sykes, J Butler, H Biernaski… - Radiology, 2020 - pubs.rsna.org
Background Despite advances, blood oxygen level–dependent (BOLD) cardiac MRI for
myocardial perfusion is limited by inadequate spatial coverage, imaging speed, multiple breath …

Reducing the dose of gadolinium-based contrast agents for DCE-MRI guided SBRT: the effects on inter and intra observer variability for preoperative target volume …

M Mouawad, H Biernaski, M Brackstone, M Lock… - Radiotherapy and …, 2019 - Elsevier
Background and purpose This study aimed to determine the effects of reducing the dose of
contrast agent (CA) in a DCE-MRI scan on inter- and intra-observer variability in the context …

The effect of registration on voxel-wise Tofts model parameters and uncertainties from DCE-MRI of early-stage breast cancer patients using 3DSlicer

M Mouawad, H Biernaski, M Brackstone, M Lock… - Journal of Digital …, 2020 - Springer
We quantitatively investigate the influence of image registration, using open-source software
(3DSlicer), on kinetic analysis (Tofts model) of dynamic contrast enhanced MRI of early-…

[HTML][HTML] Evaluation of 511 keV photon attenuation by a novel 32-channel phased array prospectively designed for cardiovascular hybrid PET/MRI imaging

…, RT Thompson, JD Thiessen, H Biernaski… - European Journal of …, 2020 - Springer
Background Simultaneous cardiovascular imaging with positron emission tomography (PET)
and magnetic resonance imaging (MRI) requires tools such as radio frequency (RF) …

PET/MRI assessment of acute cardiac inflammation 1 month after left-sided breast cancer radiation therapy

…, W Pavlosky, J Butler, H Biernaski… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Our purpose was to investigate the utility of 18 F-FDG PET/MRI and serial blood work to
detect early inflammatory responses and cardiac functionality changes at 1 mo after radiation …

[HTML][HTML] Multimodality Imaging Assessment of the Heart Before and After Stage III Non-small Cell Lung Cancer Radiation Therapy

…, A Islam, E Yu, M Qu, J Butler, H Biernaski… - Advances in Radiation …, 2022 - Elsevier
Radiation may induce unintentional injury of myocardial tissue during and after treatment of
non-small cell lung cancer (NSCLC) due to the close proximity of the heart to the target. The …