Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled …
…, E Wolin, J Tomasek, M Raderer, H Lahner… - The Lancet, 2016 - thelancet.com
Background Effective systemic therapies for patients with advanced, progressive neuroendocrine
tumours of the lung or gastrointestinal tract are scarce. We aimed to assess the efficacy …
tumours of the lung or gastrointestinal tract are scarce. We aimed to assess the efficacy …
68Ga-DOTATOC versus 68Ga-DOTATATE PET/CT in functional imaging of neuroendocrine tumors
…, I Binse, S Petersenn, H Lahner… - Journal of nuclear …, 2011 - Soc Nuclear Med
Radiolabeled somatostatin analogs represent valuable tools for both in vivo diagnosis and
therapy of neuroendocrine tumors (NETs) because of the frequent tumoral overexpression of …
therapy of neuroendocrine tumors (NETs) because of the frequent tumoral overexpression of …
Cardiovascular risk factors in patients with uncontrolled and long-term acromegaly: comparison with matched data from the general population and the effect of …
C Berg, S Petersenn, H Lahner… - The Journal of …, 2010 - academic.oup.com
Context: Data on cardiovascular risk in acromegaly are scanty and lack a clear correlation to
epidemiological data. Objective: Our aim was an evaluation of cardiovascular risk factors in …
epidemiological data. Objective: Our aim was an evaluation of cardiovascular risk factors in …
Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance
…, S Hahn, S Benson, T Dietz, H Lahner… - European Journal of …, 2007 - academic.oup.com
Objective Insulin resistance (IR) and obesity are common features of the polycystic ovary
syndrome (PCOS). Insulin-sensitizing agents have been shown to improve both reproductive …
syndrome (PCOS). Insulin-sensitizing agents have been shown to improve both reproductive …
[HTML][HTML] Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome …
S Tan, A Scherag, OE Janssen, S Hahn, H Lahner… - BMC medical …, 2010 - Springer
Background The polycystic ovary syndrome (PCOS), a common endocrine disorder in women
of child-bearing age, mainly characterised by chronic anovulation and hyperandrogenism, …
of child-bearing age, mainly characterised by chronic anovulation and hyperandrogenism, …
A phase II study of BEZ235 in patients with everolimus-resistant, advanced pancreatic neuroendocrine tumours
…, L Antonuzzo, RA Hubner, H Lahner… - Anticancer …, 2016 - ar.iiarjournals.org
Background: This was a two-stage, phase II trial of the dual phosphatidylinositol 3-kinase/mammalian
target of rapamycin inhibitor BEZ235 in patients with everolimus-resistant …
target of rapamycin inhibitor BEZ235 in patients with everolimus-resistant …
Diagnostic utility of the glucagon stimulation test in comparison to the insulin tolerance test in patients following pituitary surgery
C Berg, T Meinel, H Lahner, A Yuece… - European Journal of …, 2010 - academic.oup.com
Objective The glucagon stimulation test (GST) like the insulin tolerance test (ITT) stimulates
both ACTH and GH secretion. However, there are limited data with modern assays on …
both ACTH and GH secretion. However, there are limited data with modern assays on …
Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine …
…, J Tomasek, E Wolin, M Raderer, H Lahner… - The lancet …, 2017 - thelancet.com
Background In the phase 3 RADIANT-4 trial, everolimus increased progression-free survival
compared with placebo in patients with advanced, progressive, non-functional, well-…
compared with placebo in patients with advanced, progressive, non-functional, well-…
Evaluation of 68Ga-DOTATOC PET/MRI for whole-body staging of neuroendocrine tumours in comparison with 68Ga-DOTATOC PET/CT
…, V Ruhlmann, TD Poeppel, P Heusch, H Lahner… - European …, 2017 - Springer
Objectives To compare the diagnostic performance of 68 Ga-DOTATOC PET/MRI and 68 Ga-DOTATOC
PET/CT in the whole-body staging of patients with neuroendocrine tumours (NET…
PET/CT in the whole-body staging of patients with neuroendocrine tumours (NET…
[HTML][HTML] Treatment-related changes in neuroendocrine tumors as assessed by textural features derived from 68Ga-DOTATOC PET/MRI with simultaneous acquisition …
…, L Kessler, B Schaarschmidt, WP Fendler, H Lahner… - BMC cancer, 2020 - Springer
Background Neuroendocrine tumors (NETs) frequently overexpress somatostatin receptors (SSTRs),
which is the molecular basis for 68 Ga-DOTATOC positron-emission tomography (…
which is the molecular basis for 68 Ga-DOTATOC positron-emission tomography (…