User profiles for Hao Xu

Dr. Hao Xu

- Verified email at qti.qualcomm.com - Cited by 18762

Hao Xu

- Verified email at scu.edu.cn - Cited by 4741

Hao Xu

- Verified email at med.nyu.edu - Cited by 3399

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

Y Zhao, J Yang, J Shi, YN Gong, Q Lu, H Xu, L Liu… - Nature, 2011 - nature.com
Inflammasomes are large cytoplasmic complexes that sense microbial infections/danger
molecules and induce caspase-1 activation-dependent cytokine production and macrophage …

[HTML][HTML] High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

H Xu, L Zhong, J Deng, J Peng, H Dan… - International journal of …, 2020 - nature.com
It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a
crucial role in the entry of virus into the cell to cause the final infection. To investigate the …

[PDF][PDF] COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

…, X Wen, Q Wu, G Xu, X Xie, X Xiong, X Xing, H Xu… - Cell, 2021 - cell.com
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …

[HTML][HTML] Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

H Xu, J Yang, W Gao, L Li, P Li, L Zhang, YN Gong… - Nature, 2014 - nature.com
Cytosolic inflammasome complexes mediated by a pattern recognition receptor (PRR) defend
against pathogen infection by activating caspase 1. Pyrin, a candidate PRR, can bind to …

Spatial and temporal characteristics of 60-GHz indoor channels

H Xu, V Kukshya, TS Rappaport - IEEE Journal on selected …, 2002 - ieeexplore.ieee.org
This article presents measurement results and models for 60-GHz channels. Multipath
components were resolved in time by using a sliding correlator with 10-ns resolution and in space …

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

…, MCA Vesely, A Iseppon, L Brockmann, H Xu… - Nature, 2015 - nature.com
Inflammation is a beneficial host response to infection but can contribute to inflammatory
disease if unregulated. The Th17 lineage of T helper (Th) cells can cause severe human …

Asymmetric cooperative catalysis of strong Brønsted acid–promoted reactions using chiral ureas

H Xu, SJ Zuend, MG Woll, Y Tao, EN Jacobsen - Science, 2010 - science.org
Cationic organic intermediates participate in a wide variety of useful synthetic transformations,
but their high reactivity can render selectivity in competing pathways difficult to control. …

Enzo: An adaptive mesh refinement code for astrophysics

…, J Bordner, J Kim, M Kuhlen, H Xu… - The Astrophysical …, 2014 - iopscience.iop.org
This paper describes the open-source code Enzo, which uses block-structured adaptive mesh
refinement to provide high spatial and temporal resolution for modeling astrophysical fluid …

[HTML][HTML] The Genomes of Oryza sativa: A History of Duplications

…, H Chen, Z Xu, H Li, H Huang, F Zhang, H Xu… - PLoS …, 2005 - journals.plos.org
We report improved whole-genome shotgun sequences for the genomes of indica and
japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over the …

The phosphothreonine lyase activity of a bacterial type III effector family

H Li, H Xu, Y Zhou, J Zhang, C Long, S Li, S Chen… - Science, 2007 - science.org
Pathogenic bacteria use the type III secretion system to deliver effector proteins into host
cells to modulate the host signaling pathways. In this study, the Shigella type III effector OspF …