Assessment of 68Ga-PSMA-11 PET accuracy in localizing recurrent prostate cancer: a prospective single-arm clinical trial
Importance In retrospective studies, 68 Ga-PSMA-11 positron emission tomographic (PET)
imaging improves detection of biochemically recurrent prostate cancer compared with …
imaging improves detection of biochemically recurrent prostate cancer compared with …
Translation control of the immune checkpoint in cancer and its therapeutic targeting
Cancer cells develop mechanisms to escape immunosurveillance, among which
modulating the expression of immune suppressive messenger RNAs is most well-documented. …
modulating the expression of immune suppressive messenger RNAs is most well-documented. …
Development of a stress response therapy targeting aggressive prostate cancer
Oncogenic lesions up-regulate bioenergetically demanding cellular processes, such as protein
synthesis, to drive cancer cell growth and continued proliferation. However, the hijacking …
synthesis, to drive cancer cell growth and continued proliferation. However, the hijacking …
[HTML][HTML] The A2B adenosine receptor protects against inflammation and excessive vascular adhesion
D Yang, Y Zhang, HG Nguyen… - The Journal of …, 2006 - Am Soc Clin Investig
Adenosine has been described as playing a role in the control of inflammation, but it has not
been certain which of its receptors mediate this effect. Here, we generated an A 2B …
been certain which of its receptors mediate this effect. Here, we generated an A 2B …
Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property
HG Nguyen, D Chinnappan, T Urano… - Molecular and cellular …, 2005 - Am Soc Microbiol
The kinase Aurora-B, a regulator of chromosome segregation and cytokinesis, is highly
expressed in a variety of tumors. During the cell cycle, the level of this protein is tightly controlled, …
expressed in a variety of tumors. During the cell cycle, the level of this protein is tightly controlled, …
Diagnostic accuracy of 68Ga-PSMA-11 PET for pelvic nodal metastasis detection prior to radical prostatectomy and pelvic lymph node dissection: a multicenter …
Importance The presence of pelvic nodal metastases at radical prostatectomy is associated
with biochemical recurrence after prostatectomy. Objective To assess the accuracy of …
with biochemical recurrence after prostatectomy. Objective To assess the accuracy of …
[PDF][PDF] ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance
…, Y Wang, L Xue, E Devericks, HG Nguyen… - Cell, 2021 - cell.com
Estrogen receptor α (ERα) is a hormone receptor and key driver for over 70% of breast
cancers that has been studied for decades as a transcription factor. Unexpectedly, we discover …
cancers that has been studied for decades as a transcription factor. Unexpectedly, we discover …
Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway
The cell adhesion molecule intercellular adhesion molecule-1 (ICAM-1) plays a pivotal role
in inflammatory responses. Quercetin (3,3′,4′,5,7-pentahydroxyflavone), a naturally …
in inflammatory responses. Quercetin (3,3′,4′,5,7-pentahydroxyflavone), a naturally …
Diagnostic Accuracy of 68Ga-PSMA-11 PET/MRI Compared with Multiparametric MRI in the Detection of Prostate Cancer
Purpose To compare the diagnostic accuracy of gallium 68 ( 68 Ga)–labeled prostate-specific
membrane antigen (PSMA)–11 PET/MRI with that of multiparametric MRI in the detection …
membrane antigen (PSMA)–11 PET/MRI with that of multiparametric MRI in the detection …
Magnetic resonance imaging–ultrasound fusion biopsy during prostate cancer active surveillance
GN Tran, MS Leapman, HG Nguyen, JE Cowan… - European Urology, 2017 - Elsevier
Background Fusion biopsy using multiparametric magnetic resonance imaging (MRI) and
transrectal ultrasound has demonstrated favorable detection rates of high-grade prostate …
transrectal ultrasound has demonstrated favorable detection rates of high-grade prostate …