NEMA NU 4-2008 comparison of preclinical PET imaging systems

…, K Dinelle, E Elhami, HS Jans… - Journal of nuclear …, 2012 - Soc Nuclear Med
The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for performance
measurements of small-animal tomographs was recently published. Before this standard…

Investigation of a 3D system distortion correction method for MR images

T Stanescu, HS Jans, K Wachowicz… - Journal of applied …, 2010 - Wiley Online Library
Interest has been growing in recent years in the development of radiation treatment planning
(RTP) techniques based solely on magnetic resonance (MR) images. However, it is …

[HTML][HTML] Comparison of scandium-44 g with other PET radionuclides in pre-clinical PET phantom imaging

S Ferguson, HS Jans, M Wuest, T Riauka, F Wuest - EJNMMI physics, 2019 - Springer
Purpose The decay characteristics of radionuclides in PET studies can impact image
reconstruction. 44g Sc has been the topic of recent research due to potential theranostic …

Biodistribution and uptake of 3′-deoxy-3′-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model

RJ Paproski, M Wuest, HS Jans… - Journal of Nuclear …, 2010 - Soc Nuclear Med
18 F-3′-Deoxy-3′-fluorothymidine ( 18 F-FLT) is a PET tracer that accumulates in
proliferating tissues. The current study was undertaken to determine whether equilibrative …

Comparison of three 18F-labeled 2-nitroimidazoles for imaging hypoxia in breast cancer xenografts:[18F] FBNA,[18F] FAZA and [18F] FMISO

SN Dos Santos, M Wuest, HS Jans, J Woodfield… - Nuclear Medicine and …, 2023 - Elsevier
Background Tumour hypoxia is associated with increased metastasis, invasion, poor therapy
response and prognosis. Most PET radiotracers developed and used for clinical hypoxia …

3T MR-based treatment planning for radiotherapy of brain lesions

T Stanescu, J Hans-Sonke, P Stavrev… - Radiology and …, 2006 - radioloncol.com
Purpose. The aim of this work is to develop a complete treatment planning procedure for
radiation therapy of intracranial lesions based solely on 3T magnetic resonance imaging (MRI), …

A comparative PET imaging study of 44gSc-and 68Ga-labeled bombesin antagonist BBN2 derivatives in breast and prostate cancer models

…, J Dufour, D Krys, J Simone, HS Jans… - Nuclear Medicine and …, 2020 - Elsevier
Introduction Radiolabeled peptides play a central role in nuclear medicine as radiotheranostics
for targeted imaging and therapy of cancer. We have recently proposed the use of …

[HTML][HTML] Detecting functional changes with [18F]FAZA in a renal cell carcinoma mouse model following sunitinib therapy

DW Chapman, HS Jans, I Ma, JR Mercer, LI Wiebe… - EJNMMI research, 2014 - Springer
Background The multitargeting tyrosine kinase inhibitor (TKI) sunitinib is currently the first-line
drug therapy for metastasizing renal cell carcinoma (RCC). TKIs have profound effects on …

Delivered dose uncertainty analysis at the tumor apex for ocular brachytherapy

H Morrison, G Menon, MP Larocque, HS Jans… - Medical …, 2016 - Wiley Online Library
Purpose: To estimate the total dosimetric uncertainty at the tumor apex for ocular brachytherapy
treatments delivered using 16 mm Collaborative Ocular Melanoma Study (COMS) and …

Activity cross‐calibration of unsealed radionuclides utilizing a portable ion chamber

HS Jans - Medical Physics, 2016 - Wiley Online Library
Purpose: To present and evaluate an ion chamber‐based method for the cross‐calibration
between sites of activity measurements of unsealed radionuclides. Notably, the method …