Schizophrenia is a chronic and disabling brain disease characterized by psychotic
episodes with unknown etiology. It is suggested that neuroinflammation plays a role in the …

Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates BDNF …

Review on the key role for activated microglia and monocytes in the pathogenesis of bipolar
disorder and schizophrenia. This review describes a key role for mononuclear phagocytes …

Major depressive disorder (MDD) is a prevalent and disabling psychiatric disease with rates
of non-responsiveness to antidepressants ranging from 30–50%. Historically, the …

Background: The “monocyte-T-cell theory of mood disorders” regards neuroinflammation, ie
marked activation of microglia, as a driving force in bipolar disorder. Microglia activation can …

Background Activation of microglia cells plays an important role in neurological diseases.
Positron emission tomography (PET) with [ 11 C]-(R)-PK11195 has already been used to …

A low-grade inflammatory response is commonly seen in the peripheral blood of major
depressive disorder (MDD) patients, especially those with refractory and chronic disease courses…

Major depressive disorder is a heterogeneous disorder, mostly diagnosed on the basis of
symptomatic criteria alone. It would be of great help when specific biomarkers for various …

It is important to gain more insight into neurodegenerative diseases, because these debilitating
diseases can not be cured. A common characteristic of many neurological diseases is …

Introduction Invasive fungal infections (IFIs) occur mostly in immunosuppressed patients and
can be life-threatening. Inadequate treatment is associated with high morbidity and mortality…