[HTML][HTML] Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
dramatically expedited global vaccine development efforts 1 , 2 – 3 , most targeting the viral ‘spike’ …
dramatically expedited global vaccine development efforts 1 , 2 – 3 , most targeting the viral ‘spike’ …
[HTML][HTML] Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19
The durability of infection-induced SARS-CoV-2 immunity has major implications for reinfection
and vaccine development. Here, we show a comprehensive profile of antibody, B cell …
and vaccine development. Here, we show a comprehensive profile of antibody, B cell …
Anti-PEG antibodies boosted in humans by SARS-CoV-2 lipid nanoparticle mRNA vaccine
Humans commonly have low level antibodies to poly(ethylene) glycol (PEG) due to
environmental exposure. Lipid nanoparticle (LNP) mRNA vaccines for SARS-CoV-2 contain small …
environmental exposure. Lipid nanoparticle (LNP) mRNA vaccines for SARS-CoV-2 contain small …
[HTML][HTML] Systems serology detects functionally distinct coronavirus antibody features in children and elderly
…, P Mark Hogarth, R Esterbauer, HG Kelly… - Nature …, 2021 - nature.com
The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared
to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses, …
to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses, …
[HTML][HTML] Current and future nanoparticle vaccines for COVID-19
COVID-19 has become a major cause of global mortality and driven massive health and
economic disruptions. Mass global vaccination offers the most efficient pathway towards ending …
economic disruptions. Mass global vaccination offers the most efficient pathway towards ending …
Safety and efficacy of COVID-19 vaccines in multiple sclerosis patients
COVID-19 vaccination is recommended for multiple sclerosis patients. Disease-modifying
therapies can influence the safety and efficacy of COVID-19 vaccines. RNA, DNA, protein, and …
therapies can influence the safety and efficacy of COVID-19 vaccines. RNA, DNA, protein, and …
Immunological basis for enhanced immunity of nanoparticle vaccines
HG Kelly, SJ Kent, AK Wheatley - Expert Review of Vaccines, 2019 - Taylor & Francis
Introduction: Immunization has been a remarkably successful public health intervention;
however, new approaches to vaccine design are essential to counter existing and emerging …
however, new approaches to vaccine design are essential to counter existing and emerging …
[HTML][HTML] Immunogenicity of prime-boost protein subunit vaccine strategies against SARS-CoV-2 in mice and macaques
SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting
high titres of neutralising antibodies against the viral spike (S). However, the merits of broadly …
high titres of neutralising antibodies against the viral spike (S). However, the merits of broadly …
Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles
Recent studies have established that memory B cells, largely thought to be circulatory in the
blood, can take up long-term residency in inflamed tissues, analogous to widely described …
blood, can take up long-term residency in inflamed tissues, analogous to widely described …
Cellular interactions of liposomes and PISA nanoparticles during human blood flow in a microvascular network
A key concept in nanomedicine is encapsulating therapeutic or diagnostic agents inside
nanoparticles to prolong blood circulation time and to enhance interactions with targeted cells. …
nanoparticles to prolong blood circulation time and to enhance interactions with targeted cells. …