[HTML][HTML] Quantitative rodent brain receptor imaging

…, S Marciano, M Amend, C Parl, H Napieczynska… - Molecular Imaging and …, 2020 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology employed to
describe metabolic, physiological, and biochemical processes in vivo. These include receptor …

Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity

…, N Pashkova, C Schmidt, D Löwe, H Napieczynska… - Science …, 2022 - science.org
AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission, and
the plastic modulation of their surface levels determines synaptic strength. AMPARs of …

Mouse models of human multiple myeloma subgroups

…, E Blanc, H Napieczynska… - Proceedings of the …, 2023 - National Acad Sciences
Multiple myeloma (MM), a tumor of germinal center (GC)-experienced plasma cells, comprises
distinct genetic subgroups, such as the t(11;14)/CCND1 and the t(4;14)/MMSET subtype. …

Phosphodiesterase 3A and arterial hypertension

…, RM Illas, A Geelhaar, S Walter, H Napieczynska… - Circulation, 2020 - Am Heart Assoc
Background: High blood pressure is the primary risk factor for cardiovascular death
worldwide. Autosomal dominant hypertension with brachydactyly clinically resembles salt-resistant …

Imaging neuronal pathways with 52Mn PET: toxicity evaluation in rats

H Napieczynska, GW Severin, J Fonslet, S Wiehr… - Neuroimage, 2017 - Elsevier
Manganese in its divalent state (Mn 2+ ) has features that make it a unique tool for tracing
neuronal pathways. It is taken up and transported by neurons in an activity-dependent manner …

Rosmarinus officinalis L. leaf extract improves memory impairment and affects acetylcholinesterase and butyrylcholinesterase activities in rat brain

…, J Jodynis-Liebert, A Piasecka, H Napieczynska… - Fitoterapia, 2013 - Elsevier
Rosmarinus officinalis L. leaf as part of a diet and medication can be a valuable proposal for
the prevention and treatment of dementia. The aim of the study was to assess the effects of …

[HTML][HTML] RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models

…, I Bendix, M Serdar, H Napieczynska… - The Journal of …, 2020 - Am Soc Clin Investig
As one of the leading causes of maternal mortality worldwide, hypertensive disorders of
pregnancy remain inadequately treated (1). Preeclampsia, a subset of such disorders, occurs in …

Mutant phosphodiesterase 3A protects from hypertension-induced cardiac damage

…, S Pautz, S Schelenz, M Taube, H Napieczynska… - Circulation, 2022 - Am Heart Assoc
Background: Phosphodiesterase 3A (PDE3A) gain-of-function mutations cause hypertension
with brachydactyly (HTNB) and lead to stroke. Increased peripheral vascular resistance, …

[HTML][HTML] Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity

…, C Schmidt, D Löwe, H Napieczynska… - Science …, 2022 - ncbi.nlm.nih.gov
AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission, and
the plastic modulation of their surface levels determines synaptic strength. AMPARs of …

Impact of the arterial input function recording method on kinetic parameters in small-animal PET

H Napieczynska, A Kolb, P Katiyar… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The goal of this study was to validate the use of an MR-compatible blood sampler (BS) with
a detector system based on a lutetium oxyorthosilicate scintillator and avalanche …