The isotopes 5560 and 5760 have been evaluated for PET and SPECT imaging in several
clinical brain studies. For clinical application of cobalt, it is important to know the delivered …

Several studies have shown the feasibility of divalent cobalt (Co)-isotopes ( 55 Co and 57 Co)
in imaging of neuronal damage in stroke, multiple sclerosis, cerebral tumors and traumatic …

Methods: The potential role of@ Co@ f@ in vivo brain PET imaging was investigatedin four
patients after ischemic stroke. Resufts: PET showed uptake of 55 (@, 2+ in damaged brain tis …

Multiple sclerosis (MS) is an immune-mediated disease of the white matter in the brain that
can have a progressive course. However, the progression of relapsing-remitting (RR) MS into …

We report the in vivo evaluation (biodistribution, displacement and metabolization in blood,
brain and heart) in mice and the metabolism in blood of human volunteers of iodine-123 …

After acute cerebral stroke, the (peri-) infarct tissue is characterized by calcium (Ca)-mediated
neuronal damage and inflammatory processes. Monitoring Ca-mediated damage using …

… Henk Stevens, Christoph Van de Wiele, Patrick Santens, Hugo ML Jansen, Jacques De
Reuck, Rudy Dierckx and Jakob Korf … Jansen HML. Pruim J, Van der Vliet AM. et al …

Background: Traumatic brain injury (TBI) is usually assessed with the Glasgow Coma Scale
(GCS), CT and EEG. TBI can result from either the primary mechanical impact or secondary (…

Multiple sclerosis (MS) is predominantly a progressive immune-mediated disease of the
white matter in the brain. We used single photon emission tomography (SPET) and cobalt-57 (…

In PET studies we have shown the usefulness of cobalt radionuclides for the visualization
and quantification of ischaemic damage in stroke. In the present study, we explored 57 Co 2+ …