User profiles for H. Kim Lyerly
Herbert Kim LyerlyProfessor, Duke University Verified email at mc.duke.edu Cited by 26586 |
Anti-GP 120 antibodies from HIV seropositive individuals mediate broadly reactive anti-HIV ADCC
HKIM LYERLY, DL REED, TJ MATTHEWS… - AIDS research and …, 1987 - liebertpub.com
Cytophilic antibodies which mediate antibody dependent cellular cytotoxicity (ADCC) against
envelope antigens of human immunodeficiency virus (HIV) can be found in seropositive …
envelope antigens of human immunodeficiency virus (HIV) can be found in seropositive …
[HTML][HTML] A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
…, A Delcayre, DH Hsu, JB Le Pecq, HK Lyerly - Journal of translational …, 2005 - Springer
Background There is a continued need to develop more effective cancer immunotherapy
strategies. Exosomes, cell-derived lipid vesicles that express high levels of a narrow spectrum …
strategies. Exosomes, cell-derived lipid vesicles that express high levels of a narrow spectrum …
Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
Cells of the monocyte-macrophage lineage are targets for human immunodeficiency virus-1
(HIV-1) infection in vivo. However, many laboratory strains of HIV-1 that efficiently infect …
(HIV-1) infection in vivo. However, many laboratory strains of HIV-1 that efficiently infect …
Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex
In a 6-week clinical trial 4 dose regimens of 3'-azido-3'-deoxythymidine (AZT), a thymidine
analogue with potent anti-viral activity against HTLV-III in vitro, were examined in 19 patients …
analogue with potent anti-viral activity against HTLV-III in vitro, were examined in 19 patients …
Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA
…, D Boczkowski, M Morse, RI Cumming, HK Lyerly… - Nature …, 1998 - nature.com
Dendritic cells (DC) generated from the peripheral blood mononuclear cells of healthy
individuals or from cancer patients transfected with carcinoembryonic antigen (CEA) mRNA …
individuals or from cancer patients transfected with carcinoembryonic antigen (CEA) mRNA …
Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells
D Boczkowski, SK Nair, JH Nam, HK Lyerly, E Gilboa - Cancer research, 2000 - AACR
Unique patient-specific tumor antigens may constitute the dominant antigens in the antitumor
immune response. Hence, vaccination with the patient’s own repertoire of tumor antigens …
immune response. Hence, vaccination with the patient’s own repertoire of tumor antigens …
Migration of human dendritic cells after injection in patients with metastatic malignancies
Present clinical studies of active immunotherapy for malignancies using dendritic cells (DCs)
require elucidation of the sites where DCs localize after injection. We evaluated the pattern …
require elucidation of the sites where DCs localize after injection. We evaluated the pattern …
Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone
…, K Comatas, J Magnani, H Kim Lyerly… - Science translational …, 2016 - science.org
Breast cancer metastatic relapse can occur years after therapy, indicating that disseminated
breast cancer cells (BCCs) have a prolonged dormant phase before becoming proliferative. …
breast cancer cells (BCCs) have a prolonged dormant phase before becoming proliferative. …
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide,
but credible estimates from the World Health Organization and the International Agency for …
but credible estimates from the World Health Organization and the International Agency for …
Use of paravertebral block anesthesia in the surgical management of breast cancer: experience in 156 cases
…, JD Iglehart, GS Leight, SM Steele, HK Lyerly - Annals of …, 1998 - journals.lww.com
Objective To assess safety and efficacy of the regional anesthetic technique paravertebral
block for operative treatment of breast cancer, and to compare postoperative pain, nausea, …
block for operative treatment of breast cancer, and to compare postoperative pain, nausea, …