Context Although prostate cancer (PCa) screening reduces the incidence of advanced disease
and mortality, trade-offs include overdiagnosis and resultant overtreatment. Objective To …

CONTEXT: Prostate cancer (PCa) remains an increasingly common malignancy worldwide.
The optimal management of clinically localized, early-stage disease remains unknown, and …

Purpose : Approximately 25% of radical prostatectomies performed for stage T1c disease
show potentially insignificant prostate cancer. We previously reported the use of serum …

Objective. ——To evaluate longitudinal changes in prostate-specific antigen (PSA) levels in
men with and without prostate disease. Design. —Case-control study of men with and …

Clinical stage, Gleason score and serum prostate specific antigen (PSA) levels are used
separately to predict pathological stage in patients with localized prostate cancer. Because the …

Purpose : The guideline purpose is to provide the urologist with a framework for the early
detection of prostate cancer in asymptomatic average risk men. Materials and Methods : A …

The prostate gland is the major site of medical problems in the US male. Surgery for benign
prostatic hyperplasia is the most common surgical procedure performed in males, and the …

To evaluate the usefulness of serum prostate specific antigen in the preoperative staging of
prostate cancer we examined tumor volume and differentiation, as well as benign prostatic …

Purpose : More than 1 million prostate biopsies are performed annually among Medicare
beneficiaries. We determined the risk of serious complications requiring hospitalization. We …

Results The median survival free of intervention was 6.5 years (range, 0.0 to 15.0 years)
after diagnosis, and the proportions of men remaining free of intervention after 2, 5, and 10 …