An automated system for the production of high specific activity 64 Cu via the irradiation of
electroplated enriched 64 Ni targets has been developed. We have been operating this …

Background: Alpha-particle-emitting radiotherapies are of great interest for the treatment of
disseminated cancer. Actinium-225 ( 225 Ac) produces four α-particles through its decay and …

There remains an unmet need for molecularly targeted imaging agents for multiple myeloma
(MM). The integrin very late antigen 4 (VLA4), is differentially expressed in malignant MM …

Sodium Acetate C 11 Injection is a radiopharmaceutical commonly used for clinical studies
with positron emission tomography (PET). We have designed a fully-automated robotic …

Automated production of a promising radiopharmaceutical (−)−(1−(8−(2−[ 18 F]fluoroethoxy)-3-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-piperidin-4-yl)(4-fluorophenyl)methanone
([ …

Automated synthesis of a radiopharmaceutical 3-((2-fluoro-4-(5-(2′-methyl-2-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1,2,4-oxadiazol-3-yl)benzyl)
(methyl- 11 C)amino)propanoic acid ([ …

255 Objectives: 6-[ 18 F]Fluorodopa (FDOPA) is useful for PET studies of movement
disorders like Parkinson disease and oncological conditions like neuroblastoma. Fdopa is …

To meet a multiple-dose clinical evaluation of the P-gp modulation of [ 11 C]morphine
delivery into the human brain, radiosynthesis of [ 11 C]morphine was accomplished on an …

1591 Introduction: Molecular imaging of S1P1 expression in the brain provides an important
biomarker for elucidating the pathophysiological roles of S1P1 in neuroinflammation and …

Conclusions: This is a significant step in quantifying the discrepancy between clinically
observed toxicity and predicted toxicity based on whole organ AD values using small scale …