Indium-111-pentetreotide prolongs survival in gastroenteropancreatic malignancies

LB Anthony, EA Woltering, GD Espenan… - Seminars in nuclear …, 2002 - Elsevier
Somatostatin and its analogues bind to somatostatin receptors (sst) 1 through 5 that are
overexpressed in neuroendocrine neoplasms such as gastroenteropancreatic (GEP) …

Peptide receptor radionuclide therapy with 177Lu-DOTATATE for patients with somatostatin receptor–expressing neuroendocrine tumors: the first US phase 2 …

…, S Zamanian, EM Wolin, M Hamiditabar, GD Espenan… - Pancreas, 2014 - journals.lww.com
Objective Peptide receptor radionuclide therapy with radiolabeled somatostatin analogs is a
novel method of treatment in patients with metastatic neuroendocrine tumors (NETs). For …

In situ radiotherapy with 111In-pentetreotide: initial observations and future directions.

KE McCarthy, EA Woltering, GD Espenan… - The Cancer Journal …, 1998 - europepmc.org
Purpose Somatostatin and its analogues, such as octreotide and lanreotide, are used to treat
neuroendocrine malignancies. Somatostatin analogues bind to somatostatin receptors (sst …

[HTML][HTML] Long-term survival, toxicity profile, and role of F-18 FDG PET/CT scan in patients with progressive neuroendocrine tumors following peptide receptor …

…, JS Mourtada, S Zamanian, GD Espenan… - Theranostics, 2012 - ncbi.nlm.nih.gov
Aim: To study the long term benefits, toxicity and survival rate in patients with neuroendocrine
tumors receiving multiple cycles of high activity In-111 Pentetreotide therapy. Moreover, …

[PDF][PDF] Progressive nuclear translocation of somatostatin analogs

…, S Hughey, BM Gebhardt, GD Espenan… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Optimal cancer radiotherapy using Auger electron emitters requires selective localization of
radionuclides in close proximity to tumor DMA. Methods: Intracellular trafficking of 125l-Tyr1-…

Intraoperative Gamma Detection Of125I-Lanreotide in Women With Primary Breast Cancer

…, JC Watson, DA Wray, GD Espenan… - Annals of Surgical …, 1999 - Springer
Background: Somatostatin receptors are present in most human breast cancers. We performed
a pilot trial of intraoperative tumor-gamma detection using the radiolabeled somatostatin …

Experiences with high dose radiopeptide therapy: the health physics perspective

GD Espenan, JA Nelson, DR Fisher, DS Diaco… - Health …, 1999 - journals.lww.com
One of the new, promising areas of nuclear medicine involves radiolabeled low-molecular-weight
peptides for the diagnosis and management of cancer. Somatostatin analogous …

Multiply radioiodinated somatostatin analogs induce receptor-specific cytotoxicity

…, GJ Drouant, J Fuselier, GD Espenan… - Journal of Surgical …, 1998 - Elsevier
Background.Radiolabeled somatostatin analogs have gained popularity for tumor imaging
and have recently been used for the treatment of somatostatin receptor-expressing tumors. …

[PDF][PDF] Submitted to the Gradidate Faculty of the

GD Espenan - 1985 - creditmonitor.lsu.edu
An instrumental neutron activation analysis (INAA) method for the determination of aluminum
(Al) in fish tissue was developed to aid in the investigation of Al-caused death in fish. Six …

HIGH DOSE 111IN-PENTETREOTIDE THERAPY (SOMATOTHER™) PROLONGS SURVIVAL IN CARCINOID SYNDROME.

LB Anthony, EA Woltering, GD Espenan… - Clinical Nuclear …, 1999 - journals.lww.com
Somatostatin analogs effectively control carcinoid syndrome symptoms. Somatostatin
receptor subtype 2 (sst 2) is commonly expressed on the surface of carcinoid and other well …