The role of estrogen and its receptors in the etiology and progression of prostate cancer (PC)
is poorly understood. In normal and malignant human prostate, estrogen receptor-α is …

Prostate-specific membrane antigen (PSMA) may be targeted for both diagnostic and therapeutic
purposes in the management of prostate cancer (PCa). In preclinical models, androgen …

Objective To evaluate the ability of prostate‐specific membrane antigen ( PSMA )‐positron‐emission
tomography ( PET )/computed tomography ( CT ) to detect intermediate‐grade intra‐…

We have utilized oligonucleotide microarrays to identify novel genes of potential clinical and
biological importance in prostate cancer. RNA from 74 prostate cancers and 164 normal …

BACKGROUND Predicting outcome for men with clinically localized prostate carcinoma
treated with curative intent remains imprecise and further evaluation of accepted and potential …

BACKGROUND The role of the bone morphogenetic protein (BMP) pathway in prostate
cancer (PC) is unclear. This study aimed to characterize aspects of the BMP pathway in PC by …

BACKGROUND In the current study, the authors sought to further stratify the prognosis of
patients with Gleason score (GS) 7 prostate carcinoma. They assessed the influence on …

Purpose: Prospective studies are lacking in assessing the diagnostic utility of serial
multiparametric magnetic resonance imaging to predict biopsy proven progression to clinically …

Purpose: Activation of the Wnt-signaling pathway is implicated in aberrant cellular proliferation
in a variety of cancers. Secreted frizzled-related protein 4 (sFRP4) is a secreted protein …

β‐catenin in its role as a nuclear signaling molecule has been implicated in prostate
carcinogenesis primarily through modulation of androgen receptor activity. We defined the pattern …