Silks are naturally occurring polymers that have been used clinically as sutures for centuries.
When naturally extruded from insects or worms, silk is composed of a filament core protein, …

Biofabrication of living structures with desired topology and functionality requires the
interdisciplinary effort of practitioners of the physical, life and engineering sciences. Such efforts are …

Cardiac tissues generated from human induced pluripotent stem cells (iPSCs) can serve as
platforms for patient-specific studies of physiology and disease 1 , 2 , 3 , 4 , 5 – 6 . However, …

Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues
grown inside microfluidic chips. To better mimic human physiology, the chips are designed to …

The major challenge of tissue engineering is directing the cells to establish the physiological
structure and function of the tissue being replaced across different hierarchical scales. To …

This article summarizes the views expressed at the third session of the workshop "Tissue
Engineering—The Next Generation," which was devoted to the engineering of complex tissue …

Synthetic polymer scaffolds designed for cell transplantation were reproducibly made on a
large scale and studied with respect to biocompatibility, structure and biodegradation rate. …

Silks have a long history of biomedical use as sutures. Silk can be purified, chemically
modified to attach RGD sequences and processed into highly porous scaffolds for tissue …

Growth factors, hormones, and other regulatory molecules are traditionally required in tissue
engineering studies to direct the differentiation of progenitor cells along specific lineages. …

Angiogenesis is crucial for the success of most tissue engineering strategies. The natural
inflammatory response is a major regulator of vascularization, through the activity of different …