Cerebral dopaminergic and glutamatergic transmission relate to different subjective responses of acute alcohol intake: an in vivo multimodal imaging study
G Leurquin‐Sterk, J Ceccarini, CL Crunelle… - Addiction …, 2018 - Wiley Online Library
Converging preclinical evidence links extrastriatal dopamine release and glutamatergic
transmission via the metabotropic glutamate receptor 5 (mGluR5) to the rewarding properties of …
transmission via the metabotropic glutamate receptor 5 (mGluR5) to the rewarding properties of …
Lower limbic metabotropic glutamate receptor 5 availability in alcohol dependence
G Leurquin-Sterk, J Ceccarini… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Animal studies suggest an important role for the metabotropic glutamate receptor subtype 5 (mGlu5)
in the pathophysiology of alcohol dependence, but direct human evidence is lacking…
in the pathophysiology of alcohol dependence, but direct human evidence is lacking…
Recovery of decreased metabotropic glutamate receptor 5 availability in abstinent alcohol-dependent patients
J Ceccarini, G Leurquin-Sterk… - Journal of Nuclear …, 2020 - Soc Nuclear Med
… The group of 16 alcohol-dependent patients included in the present study was the same
as that in the study of Leurquin-Sterk et al. (7). In this subsequent study, all alcohol-dependent …
as that in the study of Leurquin-Sterk et al. (7). In this subsequent study, all alcohol-dependent …
What we observe in vivo is not always what we see in vitro: development and validation of 11C-JNJ-42491293, a novel radioligand for mGluR2
G Leurquin-Sterk, S Celen, K Van Laere… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Positive allosteric modulators (PAM) of metabotropic glutamate receptor 2 (mGluR2) are a
potential therapy for anxiety, schizophrenia, and addiction. Aside from pathophysiologic …
potential therapy for anxiety, schizophrenia, and addiction. Aside from pathophysiologic …
Recording of ictal epileptic activity using on-scalp magnetoencephalography
…, B Legros, N Gaspard, G Leurquin-Sterk… - Annals of …, 2023 - pubmed.ncbi.nlm.nih.gov
… 1 , Gil Leurquin-Sterk …
Improvement in lung diffusion by endothelin A receptor blockade at high altitude
…, JB Martinot, G Leurquin-Sterk… - Journal of applied …, 2012 - journals.physiology.org
Lung diffusing capacity has been reported variably in high-altitude newcomers and may be
in relation to different pulmonary vascular resistance (PVR). Twenty-two healthy volunteers …
in relation to different pulmonary vascular resistance (PVR). Twenty-two healthy volunteers …
Effects of alcohol exposure on the glutamatergic system: a combined longitudinal 18F‐FPEB and 1H‐MRS study in rats
B de Laat, A Weerasekera, G Leurquin‐Sterk… - Addiction …, 2019 - Wiley Online Library
To study the role of the glutamatergic system in alcohol abuse disorders, we conducted a
longitudinal study of alcohol exposure in rats. Rats were followed with 1H-magnetic resonance …
longitudinal study of alcohol exposure in rats. Rats were followed with 1H-magnetic resonance …
Glutamatergic biomarkers for cocaine addiction: a longitudinal study using MR spectroscopy and mGluR5 PET in self-administering rats
…, A Weerasekera, G Leurquin-Sterk… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Cocaine addiction is a disorder that still lacks diagnostic biomarkers or effective pharmacotherapy.
We present findings on a rat model of cocaine self-administration that was followed …
We present findings on a rat model of cocaine self-administration that was followed …
Preclinical evaluation and quantification of 18F-FPEB as a radioligand for PET imaging of the metabotropic glutamate receptor 5
B de Laat, G Leurquin-Sterk, S Celen… - Journal of Nuclear …, 2015 - Soc Nuclear Med
The metabotropic glutamate receptor 5 (mGluR5) is a high-interest target for PET imaging
because it plays a role in several pathologies, including addiction, schizophrenia, and fragile …
because it plays a role in several pathologies, including addiction, schizophrenia, and fragile …
[HTML][HTML] Voxelwise Principal Component Analysis of Dynamic [S-Methyl-11C]Methionine PET Data in Glioma Patients
…, T Metens, L Lebrun, G Leurquin-Sterk… - Cancers, 2021 - mdpi.com
Simple Summary Recent works on dynamic amino acid positron emission tomography (PET)
imaging of gliomas have highlighted characteristic behaviors of time-activity curves (TACs) …
imaging of gliomas have highlighted characteristic behaviors of time-activity curves (TACs) …