User profiles for Gert H. Kruger

Gert (HG) Kruger

Research Professor, Catalysis and Peptide Research Unit, UKZN
Verified email at ukzn.ac.za
Cited by 9794

Preclinical evaluation of 68Ga-labeled 1, 4, 7-triazacyclononane-1, 4, 7-triacetic acid-ubiquicidin as a radioligand for PET infection imaging

…, JD Venter, T Govender, GH Kruger… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Antimicrobial peptides such as ubiquicidin (UBI) are believed to differentiate between
mammalian and bacterial or fungal cells. 99m Tc-UBI29-41 was previously tested for detecting …

The science case for an orbital mission to Uranus: exploring the origins and evolution of ice giant planets

…, S Kempf, E Khalisi, K Konstantinidis, H Krüger… - Planetary and Space …, 2014 - Elsevier
Giant planets helped to shape the conditions we see in the Solar System today and they
account for more than 99% of the mass of the Sun’s planetary system. They can be subdivided …

A DFT study of the catalytic ODH of n-hexane over a cluster model of vanadium oxide

NE Damoyi, HB Friedrich, GH Kruger, DJ Willock - Molecular Catalysis, 2023 - Elsevier
Supported vanadium oxides are one of the most widely reported catalysts for the selective
oxidative dehydrogenation (ODH) of alkanes to alkenes. These vanadium oxide catalysts …

A DFT mechanistic study of the ODH of n-hexane over isolated H3VO4

NE Damoyi, HB Friedrich, GH Kruger, D Willock - Molecular Catalysis, 2018 - Elsevier
Catalytic (H 3 VO 4 ) oxidative dehydrogenation (ODH) mechanistic studies of the activation
of n-hexane have been conducted by means of Density Functional Theory (DFT). Catalytic …

Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in …

U Gerth, E Krüger, I Derré, T Msadek… - Molecular …, 1998 - Wiley Online Library
The Bacillus subtilis clpP gene, encoding the proteolytic component of the Clp or Ti protease,
was cloned and sequenced. The amount of clpP‐specific mRNA increased after heat shock…

Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans

…, D Hellwig, A Häder, T Krüger, K Gerth… - MBio, 2020 - Am Soc Microbiol
The capacity of Candida albicans to reversibly change its morphology between yeast and
filamentous stages is crucial for its virulence. Formation of hyphae correlates with the …

MurAA, catalysing the first committed step in peptidoglycan biosynthesis, is a target of Clp‐dependent proteolysis in Bacillus subtilis

H Kock, U Gerth, M Hecker - Molecular Microbiology, 2004 - Wiley Online Library
The carboxyvinyl transfer from phosphoenolpyruvate to UDP‐N‐acetylglucosamine is the
first committed step in the pathway of peptidoglycan formation. This crucial reaction for …

A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis

J Kirstein, D Zühlke, U Gerth, K Turgay… - The EMBO journal, 2005 - embopress.org
The soil bacterium Bacillus subtilis possesses a fine‐tuned and complex heat stress response
system. The repressor CtsR, whose activity is regulated by its modulators McsA and McsB, …

Fine-Tuning in Regulation of Clp Protein Content in Bacillus subtilis

U Gerth, J Kirstein, J Mostertz… - Journal of …, 2004 - Am Soc Microbiol
Clp-controlled proteolysis in Bacillus subtilis seems to play a substantial role, particularly
under stress conditions. Calibrated Western blot analyses were used to estimate the …

Clp-Dependent Proteolysis Down-Regulates Central Metabolic Pathways in Glucose-Starved Bacillus subtilis

U Gerth, H Kock, I Kusters, S Michalik… - Journal of …, 2008 - Am Soc Microbiol
Entry into stationary phase in Bacillus subtilis is linked not only to a redirection of the gene
expression program but also to posttranslational events such as protein degradation. Using …