This review summarizes the main pathophysiological basis of the relationship between
metabolic syndrome, endocrine disruptor exposure and prostate cancer that is the most common …

We measured the tissue concentration of human urokinase receptor (uPAR) in 22 breast
carcinomas and 9 benign breast lesions using in vitro quantitative autoradiography. Tissue …

The American Joint Committee on Cancer/Union Internationale Contre le Cancer ( AJCC /
UICC ) TNM staging system provides the most reliable guidelines for the routine …

Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

The prevalence of BRAF, NRAS, and p16CDKN2A mutations during melanoma progression
remains inconclusive. We investigated the prevalence and distribution of mutations in these …

Purpose: CXCR4 receptor and its unique ligand, the CXCL12 chemokine, have been recently
implicated in cancer metastasis. Evidence about the role of CXCR4/CXCL12 axis has …

Background Empagliflozin (EMPA), a selective inhibitor of the sodium glucose co-transporter
2, reduced the risk of hospitalization for heart failure and cardiovascular death in type 2 …

Background In the USA, about 30 200 well-differentiated thyroid carcinomas were diagnosed
in 2007, but the prevalence of thyroid nodules is much higher (about 5% of the adult …

Background Ipilimumab can induce durable disease control and long-term survival in patients
with metastatic melanoma. Identification of a biomarker that correlates with clinical benefit …