User profiles for Gerard R. Rutteman

Gerard R. Rutteman

retired senior investigator Univ. Utrecht, Dept. Clin. Sci. Comp. Anim. Artist Drager Meurtant
Verified email at uu.nl
Cited by 7507

[HTML][HTML] Prognostic factors for treatment of malignant lymphoma in dogs

E Teske, P van Heerde, GR Rutteman… - Journal of the …, 1994 - Am Vet Med Assoc
Pretreatment characteristics of 138 dogs with malignant lymphoma were analyzed to determine
prognostic factors associated with outcome (ie, complete response rate, time to relapse …

Progestin-induced growth hormone excess in the dog originates in the mammary gland

PJ Selman, JA Mol, GR Rutteman… - …, 1994 - academic.oup.com
In the dog endogenous progesterone and synthetic progestins may incite overproduction of
GH, resulting in acromegaly and insulin resistance. This progrestin-induced excessive GH …

Relation between habitual diet and canine mammary tumors in a case‐control study

DP Alenza, GR Rutteman, L Peña… - Journal of veterinary …, 1998 - Wiley Online Library
In the present case‐control study several dietary and nutritional factors were investigated to
determine if a relationship exists between diet and development of mammary tumors in …

Chemotherapy with cyclophosphamide, vincristine, and prednisolone (COP) in cats with malignant lymphoma: new results with an old protocol

…, R van Noort, GR Rutteman - Journal of Veterinary …, 2002 - Wiley Online Library
This retrospective study in 61 cats with malignant lymphomas examined the efficacy of a well‐established
chemotherapy protocol (cyclophosphamide, vincristine, and prednisolone […

Mitogenic stimulation of human breast cancer cells in a growth factor‐defined medium: synergistic action of insulin and estrogen

B Van Der Burg, GR Rutteman… - Journal of cellular …, 1988 - Wiley Online Library
The cooperative action of 17β‐estradiol (E 2 ) and polypeptide growth factors in stimulating
proliferation of human breast cancer cells in vitro was investigated. To prevent background …

TP53 gene mutations in canine osteosarcoma

…, M Kik, E Teske, GR Rutteman - Veterinary …, 2008 - Wiley Online Library
Objective— To investigate mutations of the TP53 gene in canine osteosarcoma (OS). Study
Design— Clinical historic cohort study. Animals— Client‐owned dogs. Methods— OS (n=59) …

The MTAP-CDKN2A Locus Confers Susceptibility to a Naturally Occurring Canine Cancer

…, M Lynch, F Galibert, M Breen, GR Rutteman… - … , biomarkers & prevention, 2012 - AACR
Background: Advantages offered by canine population substructure, combined with clinical
presentations similar to human disorders, makes the dog an attractive system for studies of …

Growth hormone mRNA in mammary gland tumors of dogs and cats.

…, A Rijinberk, GR Rutteman - The Journal of …, 1995 - Am Soc Clin Investig
We have shown recently that in the dog progestin administration results in mammary production
of immunoreactive growth hormone (GH). At present we demonstrate the expression of …

A validation of 10 feline reference genes for gene expression measurements in snap-frozen tissues

…, FM Riemers, J Rothuizen, GR Rutteman… - Veterinary immunology …, 2007 - Elsevier
For a proper determination of relative mRNA expression levels with real-time quantitative
PCR (Q-PCR) internal standards, such as the expression of reference genes, are of utmost …

Expression of growth hormone in canine mammary tissue and mammary tumors. Evidence for a potential autocrine/paracrine stimulatory loop.

…, M de Wit, WF Voorhout, GR Rutteman… - The American journal …, 1997 - ncbi.nlm.nih.gov
The role of progestins in the pathogenesis of breast cancer in women remains controversial.
To advance this discussion, we report the demonstration and localization of progestin-…