Dosimetric techniques in 90Y-microsphere therapy of liver cancer: the MIRD equations for dose calculations

SA Gulec, G Mesoloras, M Stabin - Journal of Nuclear Medicine, 2006 - Soc Nuclear Med
Therapy with 90Y-microspheres is emerging as a mainstream treatment modality in the
management of patients with primary and metastatic liver cancer (1, 2). The technique involves …

[HTML][HTML] Safety and efficacy of Y-90 microsphere treatment in patients with primary and metastatic liver cancer: the tumor selectivity of the treatment as a function of …

SA Gulec, G Mesoloras, WA Dezarn… - Journal of translational …, 2007 - Springer
Background Treatment records and follow-up data on 40 patients with primary and
metastatic liver malignancies who underwent a single whole-liver treatment with Y-90 resin …

Neutron scattered dose equivalent to a fetus from proton radiotherapy of the mother

G Mesoloras, GA Sandison, RD Stewart… - Medical …, 2006 - Wiley Online Library
Scattered neutron dose equivalent to a representative point for a fetus is evaluated in an
anthropomorphic phantom of the mother undergoing proton radiotherapy. The effect on …

[HTML][HTML] Optimization of FDG-PET/CT imaging protocol for evaluation of patients with primary and metastatic liver disease

RA Kuker, G Mesoloras, SA Gulec - International Seminars in Surgical …, 2007 - Springer
Background Accurate determination of the extrahepatic extent and intrahepatic distribution
of disease is very important in patients with primary and metastatic liver disease for deciding …

Radiomicrosphere Therapy: Nuclear Medicine Considerations, Guidelines, and Protocols.

…, R Weiner, P Flamen, G Mesoloras… - Journal of …, 2009 - search.ebscohost.com
The clinical application of radiomicrosphere therapy (RMT) using yttrium 90 ( 90 Y) microspheres
is steadily expanding. Nuclear medicine has a paramount role in the refinement of the …

Chemotherapy with Yttrium 90 Microsphere Selective Internal Radiation Treatment and Selective External Radiation Treatment in Patients with Metastatic Pancreatic …

…, C Westbrook, G Mesoloras… - Journal of …, 2009 - search.ebscohost.com
Background: Pancreatic cancer remains a disease with a poor prognosis. Historically, response
rates to chemotherapy alone remain low, and response duration lasts only months, with …

Safety and efficacy evaluation of Y-90 microsphere treatment of liver malignancies using medical internal radiation dosimetry (MIRD)

S Gulec, G Mesoloras, A Dezarn, P McNeal, A Kennedy - 2006 - Soc Nuclear Med
1812 Objectives: To evaluate the correlations of absorbed dose estimates to liver toxicity
and tumor response in patients with liver malignancies who underwent hepatic arterial Y-90 …

Efficacy of 90Y radiomicrosphere and chemotherapy combination treatment in patients with colorectal cancer liver metastases

S Gulec, M Hall, H Atkinson, G Mesoloras… - 2008 - Soc Nuclear Med
408 Objectives: To determine the relative efficacy of 90 Y radiomicrosphere therapy (RMT)
plus standard chemotherapy (chemo-RMT) compared to chemotherapy alone in patients with …

Biologic determinants of absorbed dose estimates in Y-90 microsphere treatment of hepatic malignancies: significance of tumor perfusion measured by Tc-99m MAA …

S Gulec, G Mesoloras, W Dezarn, P McNeillie… - 2007 - Soc Nuclear Med
1676 Objectives: To evaluate the biologic (anatomic and physiologic) determinants of
absorbed dose estimates, and the dose response of tumor and liver toxicity in patients with liver …

Measurement of Functional Tumor Volume for Fluorodeoxyglucose-Positive Primary and Metastatic Liver Tumors: Validation of Optimal Threshold Value Technique.

G Mesoloras, GA Sandison… - Journal of Interventional …, 2009 - search.ebscohost.com
Background: Positron emission tomography-computed tomography (PET-CT) has proven to
be an invaluable tool for disease assessment in oncology. The tumor standard uptake value (…