Multimeric cyclic RGD peptides as potential tools for tumor targeting: solid‐phase peptide synthesis and chemoselective oxime ligation
G Thumshirn, U Hersel, SL Goodman… - … –A European Journal, 2003 - Wiley Online Library
The αvβ3 integrin receptor plays an important role in human metastasis and tumor‐induced
angiogenesis. Targeting this receptor may provide information about the receptor status of …
angiogenesis. Targeting this receptor may provide information about the receptor status of …
Two-step methodology for high-yield routine radiohalogenation of peptides: 18F-labeled RGD and octreotide analogs
T Poethko, M Schottelius, G Thumshirn… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Routine application of 18 F-labeled peptides for quantitative in vivo receptor imaging of
receptor-expressing tissues and quantification of receptor status using PET is limited by the lack …
receptor-expressing tissues and quantification of receptor status using PET is limited by the lack …
Chemoselective pre-conjugate radiohalogenation of unprotected mono- and multimeric peptides via oxime formation
T Poethko, M Schottelius, G Thumshirn, M Herz… - Radiochimica …, 2004 - degruyter.com
As part of our ongoing efforts in the development of new 18 F-labeled peptides for clinical
PET imaging, a new two-step 18 F-labeling methodology based on the chemoselective oxime …
PET imaging, a new two-step 18 F-labeling methodology based on the chemoselective oxime …
Binding of small mono-and oligomeric integrin ligands to membrane-embedded integrins monitored by surface plasmon-enhanced fluorescence spectroscopy
We recently developed a binding assay format by incorporating native transmembrane
receptors into artificial phospholipid bilayers on biosensor devices for surface plasmon …
receptors into artificial phospholipid bilayers on biosensor devices for surface plasmon …
2-Aminopurine and Pyrenylethyne-Modified Uridine as Fluorescent Probes for the Investigation of Nucleic Acids and Their Interactions
MJ Rist - 2003 - mediatum.ub.tum.de
The present thesis investigates RNA-RNA and RNA-protein interactions as well as energy
and charge transfer through DNA using fluorescence detected methods. The base analogs 2-…
and charge transfer through DNA using fluorescence detected methods. The base analogs 2-…
[PDF][PDF] Application of RGD-containing peptides as imaging probes for alphavbeta3 expression
I Dijkgraaf, AJ Beer, HJ Wester - 2009 - repository.ubn.ru.nl
Integrin alphavbeta3 plays a pivotale role in tumor angiogenesis and is a receptor for the
extracellular matrix proteins with the exposed arginine-glysine-aspartic acid (RGD) tripeptide …
extracellular matrix proteins with the exposed arginine-glysine-aspartic acid (RGD) tripeptide …
Multivalente zyklische RGD-Peptide und RGD-Mimetika für den Einsatz in Tumordiagnostik und Tumortherapie
G Thumshirn - 2003 - mediatum.ub.tum.de
Die Synthese monomerer und multimerer, hoch affiner und selektiver alpha-v-beta-3-Integrinliganden
für das gezielte Adressieren der alpha-v-beta-3-exprimierenden Tumoren bei der …
für das gezielte Adressieren der alpha-v-beta-3-exprimierenden Tumoren bei der …
[CITATION][C] Synthesis and Biological Evaluation of Highly Active Nonpeptidic α‐vs. β‐3 Integrin Antagonists
G Thumshirn, GAG Sulyok, D Weber… - …, 2004 - Wiley Online Library
Monomere und multimere RGD-Peptide für die integrinvermittelte Zelladhäsion auf Biomaterialien und zur Tumordiagnose
U Hersel - 2003 - mediatum.ub.tum.de
Durch RGD-Peptide mit oberflächenadhäsiven Ankergruppen lassen sich Biomaterialoberflächen
für die integrinvermittelte Zelladhäsion erzeugen. Eine Vielzahl von monomeren und …
für die integrinvermittelte Zelladhäsion erzeugen. Eine Vielzahl von monomeren und …
Parallelsynthese von Bibliotheken nichtpeptidischer alpha-v-beta-3-Antagonisten für den Einsatz in Tumortherapie und-diagnostik
G Sulyok - 2001 - mediatum.ub.tum.de
… Georgette Thumshirn für die ständige Diskussionsbereitschaft und den wissenschaftlichen
Austausch, · Kirstin Dechantsreiter, Albert Schröder und Mona Wolff, sowie meinen Praktikan…
Austausch, · Kirstin Dechantsreiter, Albert Schröder und Mona Wolff, sowie meinen Praktikan…