Metabolites, the chemical entities that are transformed during metabolism, provide a
functional readout of cellular biochemistry. With emerging technologies in mass spectrometry, …

Recently, interest in untargeted metabolomics has become prevalent in the general
scientific community among an increasing number of investigators. The majority of these …

In rodents, obesity and aging impair nicotinamide adenine dinucleotide (NAD + )
biosynthesis, which contributes to metabolic dysfunction. Nicotinamide mononucleotide (NMN) …

The initiation and execution of cell death can be regulated by various lipids. How the levels
of environmental (exogenous) lipids impact cell death sensitivity is not well understood. We …

Metabolites offer an important unexplored complementary approach to understanding the
pluripotency of stem cells. Using MS-based metabolomics, we show that embryonic stem cells …

To the Editor: The Feature in the February issue by Scott et al. 1 on the policy challenges of
biobanking characterizes broad specimen donor informed consent as “ethically contentious.” …

Untargeted metabolomics provides a comprehensive platform for identifying metabolites
whose levels are altered between two or more populations. By using liquid chromatography …

XCMS Online ( xcmsonline.scripps.edu ) is a cloud-based informatic platform designed to
process and visualize mass-spectrometry-based, untargeted metabolomic data. Initially, the …

Bacterial biofilms in the colon alter the host tissue microenvironment. A role for biofilms in
colon cancer metabolism has been suggested but to date has not been evaluated. Using …

Although the objective of any ‘omic science is broad measurement of its constituents, such
coverage has been challenging in metabolomics because the metabolome is comprised of a …