User profiles for Gérard N. Bischof

Gérard Nisal Bischof, PhD.

University Hospital Cologne, Department of Nuclear Medicine, Germany, Institute for …
Verified email at uk-koeln.de
Cited by 2937

The aging mind: neuroplasticity in response to cognitive training

DC Park, GN Bischof - Dialogues in clinical neuroscience, 2013 - Taylor & Francis
Is it possible to enhance neural and cognitive function with cognitive training techniques?
Can we delay age-related decline in cognitive function with interventions and stave off …

The impact of sustained engagement on cognitive function in older adults: The Synapse Project

…, S Haber, A Hebrank, GN Bischof… - Psychological …, 2014 - journals.sagepub.com
In the research reported here, we tested the hypothesis that sustained engagement in learning
new skills that activated working memory, episodic memory, and reasoning over a period …

Obesity and aging: consequences for cognition, brain structure, and brain function

GN Bischof, DC Park - Psychosomatic medicine, 2015 - journals.lww.com
Objectives This review focuses on the relationship between obesity and aging and how
these interact to affect cognitive function. The topics covered are guided by the Scaffolding …

Networks of tau distribution in Alzheimer's disease

MC Hoenig, GN Bischof, J Seemiller, J Hammes… - Brain, 2018 - academic.oup.com
Gérard N Bischof , Gérard N Bischof … Finally, we compared the mean SUVRs of each TPN
between the early (n = 10) and the advanced (n = 12) Braak group. We extracted the mean …

Age trajectories of functional activation under conditions of low and high processing demands: an adult lifespan fMRI study of the aging brain

KM Kennedy, KM Rodrigue, GN Bischof, AC Hebrank… - Neuroimage, 2015 - Elsevier
We examined functional activation across the adult lifespan in 316 healthy adults aged 20–89
years on a judgment task that, across conditions, drew upon both semantic knowledge …

Impact of tau and amyloid burden on glucose metabolism in Alzheimer's disease

GN Bischof, F Jessen, K Fliessbach… - Annals of clinical …, 2016 - Wiley Online Library
In a multimodal PET imaging approach, we determined the differential contribution of neurofibrillary
tangles (measured with [ 18 F] AV ‐1451) and beta‐amyloid burden (measured with [ …

In vivo patterns of tau pathology, amyloid-β burden, and neuronal dysfunction in clinical variants of Alzheimer's disease

J Dronse, K Fliessbach, GN Bischof… - Journal of …, 2017 - content.iospress.com
The clinical heterogeneity of Alzheimer’s disease is not reflected in the rather diffuse cortical
deposition of amyloidß. We assessed the relationship between clinical symptoms, in vivo …

Association of longitudinal cognitive decline with amyloid burden in middle-aged and older adults: evidence for a dose-response relationship

…, KM Kennedy, KM Rodrigue, G Wig, GN Bischof… - JAMA …, 2017 - jamanetwork.com
Importance Presently, the clinical standard for reporting the results of an amyloid positron
emission tomography scan is to assign a dichotomous rating of positive or negative for the …

[HTML][HTML] The Synapse Project: Engagement in mentally challenging activities enhances neural efficiency

IM McDonough, S Haber, GN Bischof… - Restorative Neurology …, 2015 - content.iospress.com
Purpose: Correlational and limited experimental evidence suggests that an engaged
lifestyle is associated with the maintenance of cognitive vitality in old age. However, the …

Effects of beta-amyloid accumulation on neural function during encoding across the adult lifespan

…, MD Devous Sr, AC Hebrank, GN Bischof… - Neuroimage, 2012 - Elsevier
Limited functional imaging evidence suggests that increased beta-amyloid deposition is
associated with alterations in brain function, even in healthy older adults. However, the majority …