Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53

…, K Sasai, H Kawai, ZM Yuan, J Bondaruk, F Suzuki… - Nature …, 2004 - nature.com
Aurora kinase A (also called STK15 and BTAK) is overexpressed in many human cancers.
Ectopic overexpression of aurora kinase A in mammalian cells induces centrosome …

Multinuclearity and increased ploidy caused by overexpression of the aurora-and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells

…, H Katayama, T Ota, T Tanaka, S Odashima, F Suzuki… - Cancer research, 1998 - AACR
Aurora- and Ipl1-like midbody-associated protein (AIM-1) is a serine/threonine kinase that is
structurally related to Drosophila aurora and Saccharomyces cerevisiae Ipl1, both of which …

[HTML][HTML] AIM‐1: a mammalian midbody‐associated protein required for cytokinesis

Y Terada, M Tatsuka, F Suzuki, Y Yasuda… - The EMBO …, 1998 - embopress.org
Mitosis is a highly coordinated process that assures the fidelity of chromosome segregation.
Errors in this process result in aneuploidy which can lead to cell death or oncogenesis. In …

Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability

T Ota, S Suto, H Katayama, ZB Han, F Suzuki… - Cancer research, 2002 - AACR
Phosphorylation of histone H3 at Ser-10 is required for maintenance of properchromosome
dynamics during mitosis. AIM-1, a mammalian Ipl1/aurora kinase involved in H3 …

Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus

…, A Fahrner, M Kirsch, T Freiman, F Suzuki… - Journal of …, 2006 - Soc Neuroscience
Mesio-temporal lobe epilepsy (MTLE) is often accompanied by granule cell dispersion (GCD),
a widening of the granule cell layer. The molecular determinants of GCD are poorly …

Aurora‐C kinase is a novel chromosomal passenger protein that can complement Aurora‐B kinase function in mitotic cells

…, Y Okano, M Tatsuka, F Suzuki… - Cell motility and the …, 2004 - Wiley Online Library
The function of Aurora‐C kinase, a member of the Aurora kinase family identified in mammals,
is currently unknown. We present evidence that Aurora‐C, like Aurora‐B kinase, is a …

Properties and structure of poly (vinyl alcohol)/silica composites

…, T Yamashita, K Iwakura, F Suzuki - Journal of Applied …, 1999 - Wiley Online Library
The relationships between the properties and structure are discussed for poly(vinyl alcohol)(PVA)/silica
composites prepared through the sol‐gel process. The composites became stiff …

Increase in BDNF-mediated TrkB signaling promotes epileptogenesis in a mouse model of mesial temporal lobe epilepsy

C Heinrich, S Lähteinen, F Suzuki, L Anne-Marie… - Neurobiology of …, 2011 - Elsevier
Mesio-temporal lobe epilepsy (MTLE), the most common drug-resistant epilepsy syndrome,
is characterized by the recurrence of spontaneous focal seizures after a latent period that …

Mitotic kinase expression and colorectal cancer progression

…, T Tanaka, S Odashima, F Suzuki… - Journal of the …, 1999 - academic.oup.com
Loss of chromosomal integrity as well as genomic stability is considered to act as a driving
force during the processes of tumorigenesis and tumor progression (1–3). Recently, two …

Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.

S Satoh, H Matsumura, F Suzuki… - Proceedings of the …, 1996 - National Acad Sciences
A 6-hr continuous infusion of 2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamidoadenos
ine (CGS21680), a selective A2a-adenosine agonist, into the subarachnoid space …