Efficient fully 3-D iterative SPECT reconstruction with Monte Carlo-based scatter compensation

FJ Beekman, HWAM de Jong… - IEEE transactions on …, 2002 - ieeexplore.ieee.org
Quantitative accuracy of single photon emission computed tomography (SPECT) images is
highly dependent on the photon scatter model used for image reconstruction. Monte Carlo …

U-SPECT-I: a novel system for submillimeter-resolution tomography with radiolabeled molecules in mice

FJ Beekman, F van der Have… - Journal of Nuclear …, 2005 - Soc Nuclear Med
A major advance in biomedical science and diagnosis was accomplished with the development
of in vivo techniques to image radiolabeled molecules, but limited spatial resolution has …

A novel, SiPM-array-based, monolithic scintillator detector for PET

…, P Dendooven, H Löhner, FJ Beekman - Physics in Medicine …, 2009 - iopscience.iop.org
Silicon photomultipliers (SiPMs) are of great interest to positron emission tomography (PET),
as they enable new detector geometries, for eg, depth-of-interaction (DOI) determination, …

The pinhole: gateway to ultra-high-resolution three-dimensional radionuclide imaging

F Beekman, F van der Have - European journal of nuclear medicine and …, 2007 - Springer
Today the majority of clinical molecular imaging procedures are carried out with single-photon
emitters and gamma cameras, in planar mode and single-photon emission computed …

Design and simulation of a high-resolution stationary SPECT system for small animals

FJ Beekman, B Vastenhouw - Physics in Medicine & Biology, 2004 - iopscience.iop.org
Exciting new SPECT systems can be created by combining pinhole imaging with compact
high-resolution gamma cameras. These new systems are able to solve the problem of the …

U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging

…, JO Krah, C Ji, SG Staelens, FJ Beekman - Journal of Nuclear …, 2009 - Soc Nuclear Med
We present a new rodent SPECT system (U-SPECT-II) that enables molecular imaging of
murine organs down to resolutions of less than half a millimeter and high-resolution total-body …

Modelling the physics in the iterative reconstruction for transmission computed tomography

…, JA Fessler, W Zbijewski, FJ Beekman - Physics in Medicine …, 2013 - iopscience.iop.org
There is an increasing interest in iterative reconstruction (IR) as a key tool to improve quality
and increase applicability of x-ray CT imaging. IR has the ability to significantly reduce …

LaBr3: Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time

…, P Dendooven, H Löhner, FJ Beekman - Physics in Medicine …, 2010 - iopscience.iop.org
The use of time-of-flight (TOF) information in positron emission tomography (PET) enables
significant improvement in image noise properties and, therefore, lesion detection. Silicon …

Accelerated iterative transmission CT reconstruction using an ordered subsets convex algorithm

C Kamphuis, FJ Beekman - IEEE Transactions on Medical …, 1998 - ieeexplore.ieee.org
Iterative maximum likelihood (ML) transmission computed tomography algorithms have
distinct advantages over Fourier-based reconstruction, but unfortunately require increased …

Review and current status of SPECT scatter correction

BF Hutton, I Buvat, FJ Beekman - Physics in Medicine & Biology, 2011 - iopscience.iop.org
Detection of scattered gamma quanta degrades image contrast and quantitative accuracy of
single-photon emission computed tomography (SPECT) imaging. This paper reviews …