3-D rat brain phantom for high-resolution molecular imaging

FJ Beekman, B Vastenhouw… - Proceedings of the …, 2009 - ieeexplore.ieee.org
With the steadily improving resolution of novel small-animal single photon emission
computed tomography (SPECT) and positron emission tomography devices, highly detailed …

In vivo biodistribution of stable spherical and filamentous micelles probed by high-sensitivity SPECT

…, AC Laan, AG Denkova, G Waton, FJ Beekman… - Biomaterials …, 2016 - pubs.rsc.org
Understanding how nanoparticle properties such as size, morphology and rigidity influence
their circulation time and biodistribution is essential for the development of nanomedicine …

High-resolution 4D preclinical single-photon emission computed tomography/X-ray computed tomography imaging of technetium transport within a heterogeneous …

…, RM Ramakers, TA DeVol, FJ Beekman… - Environmental …, 2017 - ACS Publications
A dynamic 99m Tc tracer experiment was performed to investigate the capabilities of combined
preclinical single photon emission computed tomography (SPECT) and X-ray computed …

[HTML][HTML] Topographic features of nano-pores within the osteochondral interface and their effects on transport properties–a 3D imaging and modeling study

…, V Arbabi, RLAW Bleys, FJ Beekman… - Journal of …, 2021 - Elsevier
Recent insights suggest that the osteochondral interface plays a central role in maintaining
healthy articulating joints. Uncovering the underlying transport mechanisms is key to the …

Similarity-Regulated OSEM reconstruction for pinhole-PET.

P Vaissier, M Goorden, F Beekman - 2015 - Soc Nuclear Med
48 Objectives Ordered Subsets Expectation Maximization (OSEM) is used to accelerate
tomographic reconstruction. The speed-up of OSEM over Maximum Likelihood Expectation …

U-SPECT-II: A versatile sub-half-mm resolution small animal SPECT system

F van der Have, B Vastenhouw, F Beekman - 2007 - Soc Nuclear Med
159 Objectives: To present a user friendly and versatile small animal SPECT system (U-SPECT-II)
with unsurpassed resolution in murine and rat imaging tasks, both for focused and …

Sub-half mm rat brain SPECT with a dedicated ultra-high resolution focusing pinhole collimator

F Beekman, F van der Have, B Vastenhouw - 2008 - Soc Nuclear Med
1691 Objectives: U-SPECT-II is a high resolution animal scanner consisting of stationary
detectors with exchangeable general purpose (GP) cylindrical collimators to facilitate high …

High resolution tomography of positron emitters using highly focused pinhole collimation

F Beekman, F van der Have - 2007 - Soc Nuclear Med
312 Objectives: With SPECT using stationary NaI detectors and highly focussed multi-pinhole
(HFMP) collimators (U-SPECT-I & II) sub-half mm resolution images can be obtained. Here …

Quarter-mm molecular bone imaging with a stationary high-resolution SPECT system

…, J Villena, R Ramakers, H Weinans, F Beekman - 2014 - Soc Nuclear Med
2141 Objectives With sufficient tracer uptake very high resolution SPECT can be obtained
with small pinholes. Recently we designed a new focused ultra-high-resolution collimator with …

Validation of fast marker-free image registration for small-animal SPECT/CT using a pre-calculated transformation

…, R Ramakers, B Vastenhouw, F Beekman - 2009 - Soc Nuclear Med
299 Objectives To develop and validate a convenient and robust method of co-registration
between small-animal imaging systems, based on transferrable animal beds, and requiring …